iPTMnet Report for Q00688 (FKBP3)
Protein Information
| UniProt AC / UniProt ID | Q00688 / FKBP3_HUMAN |
| Protein Name | Peptidyl-prolyl cis-trans isomerase FKBP3 |
| Gene Name | Name: FKBP3 Synonyms:FKBP25; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q00688 |
| PRO Name | peptidyl-prolyl cis-trans isomerase FKBP3 (human) |
| Definition | A peptidyl-prolyl cis-trans isomerase FKBP3 that is encoded in the genome of human. |
| Short Label | hFKBP3 |
| Category | organism-gene |
DAG ViewQ00688 (FKBP3) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 19413330, 22814378, 25944712 | ||
| T11 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R16 | Methylation | score1 | PhosphoSitePlus | |||
| K27 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S34 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S36 | Phosphorylation | score4 | HPRD PhosphoSitePlus RLIMS-P UniProt | 29361176, 17081983, 20068231 | ||
| K42 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K48 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K73 | Acetylation | score1 | PhosphoSitePlus | |||
| T75 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S77 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
| S79 | Phosphorylation | score0 | HPRD | 20068231 | ||
| K80 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S82 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K86 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T98 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 29361176 | ||
| S100 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 29361176 | ||
| T103 | Phosphorylation | score0 | RLIMS-P | 29361176 | ||
| K110 | Acetylation | score1 | PhosphoSitePlus | |||
| T147 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S152 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
| K154 | Acetylation | score1 | PhosphoSitePlus | |||
| K160 | Acetylation | score1 | PhosphoSitePlus | |||
| K160 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S163 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K165 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K170 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
| K170 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R173 | Methylation | score1 | PhosphoSitePlus | |||
| T181 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
| S183 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
| K187 | Methylation | score1 | PhosphoSitePlus | |||
| Y198 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
| K200 | Acetylation | score1 | PhosphoSitePlus | |||
| K200 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K207 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| A2 | T2 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K27 | E27 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S36 | W36 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S79 | G79 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| K80 | T80 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| K86 | N86 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| T147 | A147 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| K154 | N154 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| K160 | R160 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| K207 | R207 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |
