iPTMnet Report for Q00325 (SLC25A3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q00325 / S25A3_HUMAN
Protein Name Solute carrier family 25 member 3 precursor
Gene Name Name: SLC25A3
Synonyms:PHC;ORFNames:OK/SW-cl.48;
Organism Homo sapiens (Human)

PRO ID PR:Q00325
DAG View
PRO Name phosphate carrier protein, mitochondrial (human)
Definition A phosphate carrier protein, mitochondrial that is encoded in the genome of human.
Short Label hSLC25A3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q00325 (SLC25A3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation PhosphoSitePlus
S32 Phosphorylation PhosphoSitePlus
S33 Phosphorylation PhosphoSitePlus
Y55 Phosphorylation PhosphoSitePlus
S56 Phosphorylation PhosphoSitePlus
K99 Acetylation PhosphoSitePlus   UniProt 19608861
K99 Ubiquitination PhosphoSitePlus
Y100 Phosphorylation PhosphoSitePlus
K101 Ubiquitination PhosphoSitePlus
S108 Phosphorylation PhosphoSitePlus
T110 Phosphorylation PhosphoSitePlus
K112 Methylation PhosphoSitePlus   UniProt 24129315
K112 Ubiquitination PhosphoSitePlus
R117 Methylation PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus
Y141 Phosphorylation PhosphoSitePlus
T157 Phosphorylation PhosphoSitePlus
Y158 Phosphorylation PhosphoSitePlus
S163 Phosphorylation IEDB 30784271
Y196 Phosphorylation PhosphoSitePlus   UniProt 19369195
T199 Phosphorylation PhosphoSitePlus
R201 Methylation PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
K209 Acetylation PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
K214 Acetylation PhosphoSitePlus
K214 Ubiquitination PhosphoSitePlus
K218 Acetylation PhosphoSitePlus
K218 Ubiquitination PhosphoSitePlus
R226 Methylation PhosphoSitePlus
K234 Acetylation PhosphoSitePlus
K234 Ubiquitination PhosphoSitePlus
Y246 Phosphorylation PhosphoSitePlus
K247 Acetylation PhosphoSitePlus
K247 Ubiquitination PhosphoSitePlus
K252 Ubiquitination PhosphoSitePlus
C257 Methylation IEDB 31844290
K295 Ubiquitination PhosphoSitePlus
S297 Phosphorylation PhosphoSitePlus
S298 Phosphorylation PhosphoSitePlus
K304 Acetylation PhosphoSitePlus
K304 Ubiquitination PhosphoSitePlus
K309 Acetylation PhosphoSitePlus
K355 Acetylation PhosphoSitePlus
K355 Ubiquitination PhosphoSitePlus
K356 Acetylation PhosphoSitePlus
K357 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S108 Phosphorylation HPRD 20068231
T110 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
Y54 Phosphorylation PhosphoSitePlus
K89 Methylation PhosphoSitePlus
K98 Acetylation PhosphoSitePlus
S107 Phosphorylation HPRD 20068231
T109 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K98 Q98 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K99 Q99 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
R117 C117 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1725 / peritoneum cancer [ cosmic ]
Y196 N196 Biomuta DOID:4159 / skin cancer [ cosmic ]
T199 S199 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R201 M201 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K209 N209 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K218 M218 Biomuta DOID:263 / kidney cancer [ cosmic ]
C257 R257 Biomuta DOID:1612 / breast cancer [ cosmic ]
K295 Q295 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K304 M304 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K357 Q357 Biomuta DOID:10534 / stomach cancer [ cosmic ]