iPTMnet Report for P99999 (CYCS)
Protein Information
UniProt AC / UniProt ID | P99999 / CYC_HUMAN |
Protein Name | Cytochrome c |
Gene Name | Name: CYCS Synonyms:CYC; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P99999 |
PRO Name | cytochrome c (human) |
Definition | A cytochrome c, somatic that is encoded in the genome of human. |
Short Label | hCYCS |
Category | organism-gene |
P99999 (CYCS) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
G2 | Acetylation | score2 | UniProt | 13933734 | ||
K8 | Acetylation | score1 | PhosphoSitePlus | |||
K9 | Acetylation | score1 | PhosphoSitePlus | |||
M13 | Methylation | score2 | IEDB | 28855257 | ||
K28 | Sumoylation | score1 | PhosphoSitePlus | |||
K28 | Ubiquitination | score1 | PhosphoSitePlus | |||
T29 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
K40 | Ubiquitination | score1 | PhosphoSitePlus | |||
T41 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y47 | Phosphorylation | score1 | PhosphoSitePlus | |||
S48 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y49 | Phosphorylation | score1 | PhosphoSitePlus | |||
T50 | Phosphorylation | score1 | PhosphoSitePlus | |||
K54 | Acetylation | score1 | PhosphoSitePlus | |||
K54 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y68 | Phosphorylation | score1 | PhosphoSitePlus | |||
K73 | Acetylation | score1 | PhosphoSitePlus | |||
K73 | Ubiquitination | score1 | PhosphoSitePlus | |||
K74 | Acetylation | score1 | PhosphoSitePlus | |||
K74 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y75 | Phosphorylation | score1 | PhosphoSitePlus | |||
T79 | Phosphorylation | score1 | PhosphoSitePlus | |||
K80 | Ubiquitination | score1 | PhosphoSitePlus | |||
K87 | Acetylation | score1 | PhosphoSitePlus | |||
K87 | Ubiquitination | score1 | PhosphoSitePlus | |||
K88 | Acetylation | score1 | PhosphoSitePlus | |||
K89 | Acetylation | score1 | PhosphoSitePlus | |||
Y98 | Phosphorylation | score1 | PhosphoSitePlus | |||
K100 | Acetylation | score1 | PhosphoSitePlus | |||
K100 | Methylation | score1 | PhosphoSitePlus | |||
K100 | Ubiquitination | score1 | PhosphoSitePlus | |||
K101 | Methylation | score1 | PhosphoSitePlus |
PTM-dependent PPI
PTM type | Substrate | Site | Interactant | Association type | Source | PMID | |
---|---|---|---|---|---|---|---|
Phosphorylation | P04637 (TP53) | S46 | P99999 (CYCS) | unknown | eFIP | 19521340 | |
Phosphorylation | P04792 (HSPB1) | S78 | P99999 (CYCS) | unknown | eFIP | 22974980 |
Proteoform PPIs
Protein 1 | Relation | Protein 2 | Source | PMID | |
---|---|---|---|---|---|
PR:P99999-1 (hCYCS/iso:1) | Interaction | PR:O14727-3 (hAPAF1/iso:3) | PRO | 9267021 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
G2 | R2 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
G2 | S2 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K9 | N9 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S48 | P48 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K54 | M54 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |