iPTMnet Report for P98194 (ATP2C1)
Protein Information
| UniProt AC / UniProt ID | P98194 / AT2C1_HUMAN |
| Protein Name | Calcium-transporting ATPase type 2C member 1 |
| Gene Name | Name: ATP2C1 Synonyms:KIAA1347,PMR1L;ORFNames:HUSSY-28; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P98194 |
| PRO Name | calcium-transporting ATPase type 2C member 1 (human) |
| Definition | A calcium-transporting ATPase type 2C member 1 that is encoded in the genome of human. |
| Short Label | hATP2C1 |
| Category | organism-gene |
P98194 (ATP2C1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K2 | Acetylation | score1 | IEDB | 34357683 | ||
| K8 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T22 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S23 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K25 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S77 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K146 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S182 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C195 | Methylation | score1 | IEDB | 31844290 | ||
| K229 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T420 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K424 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T426 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K449 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y452 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K488 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K496 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K514 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S519 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T557 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T558 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S582 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K589 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S608 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S621 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K630 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K634 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S637 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T804 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S825 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S826 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K831 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K897 | Acetylation | score1 | PhosphoSitePlus | |||
| K907 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S913 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S914 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T420 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S911 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S914 | Phosphorylation | score0 | HPRD | 18669648, 20068231 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S70 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K514 | Q514 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S519 | L519 | Biomuta | DOID:3571 / liver cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| T558 | P558 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| T558 | A558 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| K589 | N589 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S637 | L637 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] | |
| K831 | T831 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
| S911 | * | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S911 | L911 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:4362 / cervical cancer [ cosmic, icgc ] | |
| S913 | L913 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:363 / uterine cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic ] DOID:4362 / cervical cancer [ cosmic, icgc ] |
DAG View