iPTMnet Report for P98175 (RBM10)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P98175 / RBM10_HUMAN
Protein Name RNA-binding protein 10
Gene Name Name: RBM10
Synonyms:DXS8237E,GPATC9,GPATCH9,KIAA0122;
Organism Homo sapiens (Human)

PRO ID PR:P98175
DAG View
PRO Name RNA-binding protein 10 (human)
Definition An RNA-binding protein 10 that is encoded in the genome of human.
Short Label hRBM10
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P98175 (RBM10) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
E2 Acetylation UniProt 21406692, 20068231
Y16 Phosphorylation PhosphoSitePlus
T19 Phosphorylation PhosphoSitePlus
S22 Phosphorylation PhosphoSitePlus
R30 Phosphorylation UniProt 18669648, 21406692, 20068231
S31 O-Glycosylation GlyGen 33214551, 35138101, 30379171, ...34725712, 30059200, 35254053, 34019948, 32119511, 28510447, 33465208
S31 Phosphorylation PhosphoSitePlus
Y36 Phosphorylation PhosphoSitePlus
Y41 Phosphorylation PhosphoSitePlus
Y44 Phosphorylation PhosphoSitePlus
Y48 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S50 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
Y57 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S60 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332, 18669648
S61 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S65 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S69 Phosphorylation PhosphoSitePlus
S73 Phosphorylation PhosphoSitePlus
S76 Phosphorylation PhosphoSitePlus
T78 Phosphorylation PhosphoSitePlus
S89 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231, 24275569
T91 Phosphorylation PhosphoSitePlus
Y107 Phosphorylation PhosphoSitePlus
T109 Phosphorylation PhosphoSitePlus
K126 Sumoylation PhosphoSitePlus
R134 Methylation PhosphoSitePlus
R146 Methylation PhosphoSitePlus
R171 Methylation PhosphoSitePlus
S194 Phosphorylation PhosphoSitePlus
S207 Phosphorylation PhosphoSitePlus
K246 Sumoylation PhosphoSitePlus
K246 Ubiquitination PhosphoSitePlus
S266 Phosphorylation PhosphoSitePlus
Y276 Phosphorylation PhosphoSitePlus
S288 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
S294 Phosphorylation PhosphoSitePlus
T312 Phosphorylation PhosphoSitePlus
K383 Acetylation UniProt 19608861
K383 Ubiquitination PhosphoSitePlus
S447 Phosphorylation PhosphoSitePlus
T469 Phosphorylation PhosphoSitePlus
T471 Phosphorylation PhosphoSitePlus
T476 Phosphorylation PhosphoSitePlus
S497 Phosphorylation PhosphoSitePlus
S516 Phosphorylation PhosphoSitePlus
S517 O-Glycosylation GlyGen 33214551, 35138101, 30379171, ...34725712, 30059200, 35254053, 34019948, 32119511, 28510447, 33465208
S517 Phosphorylation PhosphoSitePlus
T520 Phosphorylation PhosphoSitePlus
S531 Phosphorylation PhosphoSitePlus
K536 Sumoylation PhosphoSitePlus
S541 Phosphorylation PhosphoSitePlus
S546 Phosphorylation PhosphoSitePlus
S547 Phosphorylation PhosphoSitePlus
T553 Phosphorylation PhosphoSitePlus
S554 Phosphorylation PhosphoSitePlus
T556 Phosphorylation PhosphoSitePlus
S622 Phosphorylation PhosphoSitePlus
T629 Phosphorylation PhosphoSitePlus
S633 Phosphorylation PhosphoSitePlus
K653 Acetylation PhosphoSitePlus
S661 Phosphorylation PhosphoSitePlus
S687 Phosphorylation PhosphoSitePlus
Y694 Phosphorylation PhosphoSitePlus
T709 Phosphorylation PhosphoSitePlus
S710 Phosphorylation PhosphoSitePlus
S718 Phosphorylation PhosphoSitePlus   UniProt 21406692, 20068231, 24275569
S723 O-Glycosylation GlyGen 33214551, 35138101, 30379171, ...34725712, 30059200, 35254053, 34019948, 32119511, 28510447, 33465208
S723 Phosphorylation PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...18669648, 24275569, 20068231
Y732 Phosphorylation PhosphoSitePlus
S733 Phosphorylation PhosphoSitePlus   UniProt 18669648, 19690332
S736 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 18669648, ...24275569, 19690332
S738 Phosphorylation PhosphoSitePlus   UniProt 20068231, 18669648, 19690332, ...24275569
S781 Phosphorylation PhosphoSitePlus   UniProt 20068231
S797 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...19690332, 20068231
Y825 Phosphorylation PhosphoSitePlus
S845 Phosphorylation PhosphoSitePlus   UniProt 23186163
S858 Phosphorylation PhosphoSitePlus
K881 Methylation PhosphoSitePlus
K881 Sumoylation PhosphoSitePlus
K881 Ubiquitination PhosphoSitePlus
T886 Phosphorylation PhosphoSitePlus
R895 Methylation PhosphoSitePlus
R902 Methylation PhosphoSitePlus   UniProt 24129315
S904 Phosphorylation PhosphoSitePlus
S905 Phosphorylation PhosphoSitePlus
T911 O-Glycosylation GlyGen 33214551, 35138101, 30379171, ...34725712, 30059200, 35254053, 34019948, 32119511, 28510447, 33465208
S913 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y48 Phosphorylation HPRD 18669648
S50 Phosphorylation HPRD 17525332, 20068231
Y57 Phosphorylation HPRD 18669648
S60 Phosphorylation HPRD 17525332, 18669648, 18452278
S61 Phosphorylation HPRD 18669648, 18452278
S65 Phosphorylation HPRD 18669648, 18452278
S73 Phosphorylation HPRD 18452278
S76 Phosphorylation HPRD 18452278
S89 Phosphorylation HPRD 17322306, 18767875, 18452278, ...19651622, 18707149, 20166139, 20068231
T91 Phosphorylation HPRD 17322306, 18767875, 19651622, ...20068231
S288 Phosphorylation HPRD 17525332
S517 Phosphorylation HPRD 17525332, 18077418
S718 Phosphorylation HPRD 19651622, 19664995, 20068231
S723 Phosphorylation HPRD 18691976, 17287340, 18767875, ...19664995, 18452278, 19651622, 17322306, 18669648, 20166139, 19415658, 20068231
Y732 Phosphorylation HPRD 17081983, 18452278
S733 Phosphorylation HPRD 19413330, 18691976, 17081983, ...18452278, 19651622, 18669648, 20187088, 20068231
S736 Phosphorylation HPRD 19413330, 18691976, 18767875, ...15302935, 18452278, 19651622, 18669648, 20187088, 20166139, 15345747, 20068231
S738 Phosphorylation HPRD 19413330, 18691976, 18767875, ...19651622, 18452278, 17322306, 18669648, 20187088, 20166139, 19415658, 20068231
S781 Phosphorylation HPRD 20068231
S797 Phosphorylation HPRD 17322306, 18767875, 18452278, ...19651622, 18669648, 20068231
T886 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
Y16 Phosphorylation P12931 (SRC) PhosphoSitePlus 18698806
Y36 Phosphorylation PhosphoSitePlus
Y41 Phosphorylation PhosphoSitePlus
Y48 Phosphorylation PhosphoSitePlus
S50 Phosphorylation PhosphoSitePlus
Y57 Phosphorylation PhosphoSitePlus
S61 Phosphorylation PhosphoSitePlus
S65 Phosphorylation PhosphoSitePlus
Y70 Phosphorylation PhosphoSitePlus
S73 Phosphorylation PhosphoSitePlus
S89 Phosphorylation PhosphoSitePlus
T91 Phosphorylation PhosphoSitePlus
S166 Phosphorylation PhosphoSitePlus
S288 Phosphorylation PhosphoSitePlus
K382 Acetylation PhosphoSitePlus
Y434 Phosphorylation P12931 (SRC) PhosphoSitePlus 18698806
K652 Acetylation PhosphoSitePlus
Y693 Phosphorylation PhosphoSitePlus
S717 Phosphorylation PhosphoSitePlus
S722 Phosphorylation PhosphoSitePlus
S732 Phosphorylation PhosphoSitePlus
S735 Phosphorylation PhosphoSitePlus
S737 Phosphorylation PhosphoSitePlus
S780 Phosphorylation PhosphoSitePlus
S796 Phosphorylation PhosphoSitePlus
Y824 Phosphorylation PhosphoSitePlus
T885 Phosphorylation PhosphoSitePlus
R901 Methylation PhosphoSitePlus
S904 Phosphorylation PhosphoSitePlus
Y905 Phosphorylation P12931 (SRC) PhosphoSitePlus 18698806
Site PTM Type PTM Enzyme Score Source PMID
S50 Phosphorylation PhosphoSitePlus
S60 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S50 Phosphorylation HPRD 20068231
S211 Phosphorylation HPRD 17525332
S439 Phosphorylation HPRD 17525332, 18077418
S640 Phosphorylation HPRD 19651622, 19664995, 20068231
S645 Phosphorylation HPRD 18691976, 17287340, 18767875, ...19664995, 18452278, 19651622, 17322306, 18669648, 20166139, 19415658, 20068231
Y654 Phosphorylation HPRD 17081983, 18452278
S655 Phosphorylation HPRD 19413330, 18691976, 17081983, ...18452278, 19651622, 18669648, 20187088, 20068231
S658 Phosphorylation HPRD 19413330, 18691976, 18767875, ...15302935, 18452278, 19651622, 18669648, 20187088, 20166139, 15345747, 20068231
S660 Phosphorylation HPRD 19413330, 18691976, 18767875, ...19651622, 18452278, 17322306, 18669648, 20187088, 20166139, 19415658, 20068231
S703 Phosphorylation HPRD 20068231
S719 Phosphorylation HPRD 17322306, 18767875, 18452278, ...19651622, 18669648, 20068231
T808 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation PhosphoSitePlus
S15 Phosphorylation PhosphoSitePlus
S25 Phosphorylation PhosphoSitePlus
S30 Phosphorylation PhosphoSitePlus
S38 Phosphorylation PhosphoSitePlus
Y68 Phosphorylation PhosphoSitePlus
S581 Phosphorylation PhosphoSitePlus
S582 Phosphorylation PhosphoSitePlus
T585 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
E2 K2 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
E2 G2 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
Y16 C16 Biomuta DOID:3571 / liver cancer [ cosmic ]
S25 F25 Biomuta [ cosmic ]
R30 H30 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic ]
R30 C30 Biomuta DOID:363 / uterine cancer [ icgc ]
Y36 C36 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y44 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S60 * Biomuta DOID:263 / kidney cancer [ cosmic ]
R146 C146 Biomuta [ cosmic ]
R171 Q171 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
R171 W171 Biomuta DOID:4159 / skin cancer [ cosmic, icgc, tcga ] DOID:3119 / gastrointestinal system cancer [ cosmic ]
S211 * Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
S288 * Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
S439 N439 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
T469 N469 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S517 N517 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
S531 * Biomuta DOID:263 / kidney cancer [ cosmic ]
S531 L531 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S541 N541 Biomuta DOID:1324 / lung cancer [ cosmic ]
S546 I546 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S554 R554 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T556 S556 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S582 N582 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
S622 * Biomuta [ cosmic ]
T629 I629 Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S633 L633 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
K653 N653 Biomuta DOID:363 / uterine cancer [ cosmic ]
S660 I660 Biomuta DOID:1324 / lung cancer [ cosmic ]
S687 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
Y694 N694 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
S703 * Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S703 L703 Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
T709 A709 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S710 I710 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S710 N710 Biomuta DOID:3571 / liver cancer [ cosmic ]
S719 L719 Biomuta DOID:1324 / lung cancer [ cosmic ]
S738 I738 Biomuta DOID:1324 / lung cancer [ cosmic ]
S781 * Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S781 L781 Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc, tcga ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S797 L797 Biomuta DOID:1324 / lung cancer [ cosmic ]
T808 M808 Biomuta DOID:263 / kidney cancer [ cosmic ]
Y825 C825 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T886 M886 Biomuta DOID:263 / kidney cancer [ cosmic ]
R895 W895 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
R902 W902 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:263 / kidney cancer [ cosmic ]