iPTMnet Report for P98172 (EFNB1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P98172 / EFNB1_HUMAN
Protein Name Ephrin-B1 precursor
Gene Name Name: EFNB1
Synonyms:EFL3,EPLG2,LERK2;
Organism Homo sapiens (Human)

PRO ID PR:P98172
DAG View
PRO Name ephrin-B1 (human)
Definition An ephrin-B1 that is encoded in the genome of human.
Short Label hEFNB1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P98172 (EFNB1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y79 Phosphorylation PhosphoSitePlus
N139 N-Glycosylation GlyGen 23090970, 29779877, 24190977
K163 Ubiquitination PhosphoSitePlus
T172 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T177 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T178 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S179 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T188 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T193 O-Glycosylation GlyGen 25813380
S201 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T211 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S218 Phosphorylation PhosphoSitePlus
S223 Phosphorylation PhosphoSitePlus
S226 Phosphorylation PhosphoSitePlus
S227 Phosphorylation PhosphoSitePlus
S281 Phosphorylation PhosphoSitePlus   UniProt 23186163
S283 Phosphorylation PhosphoSitePlus
T284 Phosphorylation HPRD 20068231
S287 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
K289 Ubiquitination PhosphoSitePlus
Y313 Phosphorylation HPRD   PhosphoSitePlus 17016520
Y317 Phosphorylation HPRD   PhosphoSitePlus 17016520, 17389395
K319 Ubiquitination PhosphoSitePlus
S321 Phosphorylation PhosphoSitePlus
Y324 Phosphorylation HPRD   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P 20565770, 11466320, 25436983
Y329 Phosphorylation HPRD   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P 20565770, 11466320, 25436983
S338 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y343 Phosphorylation HPRD   phospho.ELM   PRO   PhosphoSitePlus 17016520, 11466320
Y344 Phosphorylation PhosphoSitePlus
K345 Ubiquitination PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000047255 (hEFNB1/SigPep-/Phos:1) pY324,pY329,pY343 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S201 F201 Biomuta DOID:4159 / skin cancer [ cosmic ]
S287 N287 Biomuta [ cosmic ]
S321 T321 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S321 C321 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
Y324 C324 Biomuta DOID:10534 / stomach cancer [ icgc ]
Y329 H329 Biomuta DOID:4606 / bile duct cancer [ cosmic ]