iPTMnet Report for P98155 (VLDLR)
Protein Information
| UniProt AC / UniProt ID | P98155 / VLDLR_HUMAN |
| Protein Name | Very low-density lipoprotein receptor precursor |
| Gene Name | Name: VLDLR |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P98155 |
| PRO Name | very low-density lipoprotein receptor (human) |
| Definition | A very low-density lipoprotein receptor that is encoded in the genome of human. |
| Short Label | hVLDLR |
| Category | organism-gene |
P98155 (VLDLR) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T71 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 30459171 | ||
| T192 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| T277 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 30459171 | ||
| Y524 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S759 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K828 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y837 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K839 | Ubiquitination | score3 | PRO PhosphoSitePlus UniProt | 20427281 | ||
| S846 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y860 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S867 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T868 | Phosphorylation | score1 | PhosphoSitePlus |
Proteoforms
| PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
|---|---|---|---|---|---|
| PR:000049661 (hVLDLR/SigPep-/Ubiq:1) | ubK839 | PRO |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T71 | M71 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] | |
| T71 | A71 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S846 | Y846 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] |
DAG View