iPTMnet Report for P98155 (VLDLR)
Protein Information
UniProt AC / UniProt ID | P98155 / VLDLR_HUMAN |
Protein Name | Very low-density lipoprotein receptor precursor |
Gene Name | Name: VLDLR |
Organism | Homo sapiens (Human) |
PRO ID | PR:P98155 |
PRO Name | very low-density lipoprotein receptor (human) |
Definition | A very low-density lipoprotein receptor that is encoded in the genome of human. |
Short Label | hVLDLR |
Category | organism-gene |
P98155 (VLDLR) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T71 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 30459171 | ||
T192 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
T277 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 30459171 | ||
Y524 | Phosphorylation | score1 | PhosphoSitePlus | |||
S759 | Phosphorylation | score1 | PhosphoSitePlus | |||
K828 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y837 | Phosphorylation | score1 | PhosphoSitePlus | |||
K839 | Ubiquitination | score3 | PRO PhosphoSitePlus UniProt | 20427281 | ||
S846 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y860 | Phosphorylation | score1 | PhosphoSitePlus | |||
S867 | Phosphorylation | score1 | PhosphoSitePlus | |||
T868 | Phosphorylation | score1 | PhosphoSitePlus |
Proteoforms
PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
---|---|---|---|---|---|
PR:000049661 (hVLDLR/SigPep-/Ubiq:1) | ubK839 | PRO |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T71 | M71 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] | |
T71 | A71 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S846 | Y846 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] |