Protein Information

Cytoscape View


UniProt AC / UniProt ID P98155 / VLDLR_HUMAN
Protein Name Very low-density lipoprotein receptor precursor
Gene Name Name: VLDLR
Organism Homo sapiens (Human)

PRO ID PR:P98155
DAG View
PRO Name very low-density lipoprotein receptor (human)
Definition A very low-density lipoprotein receptor that is encoded in the genome of human.
Short Label hVLDLR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P98155 (VLDLR) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T71 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
T192 O-Glycosylation GlyGen 30459171
T277 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
Y524 Phosphorylation PhosphoSitePlus
S759 Phosphorylation PhosphoSitePlus
K828 Ubiquitination PhosphoSitePlus
Y837 Phosphorylation PhosphoSitePlus
K839 Ubiquitination PRO   PhosphoSitePlus   UniProt 20427281
S846 Phosphorylation PhosphoSitePlus
Y860 Phosphorylation PhosphoSitePlus
S867 Phosphorylation PhosphoSitePlus
T868 Phosphorylation PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000049661 (hVLDLR/SigPep-/Ubiq:1) ubK839 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T71 M71 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
T71 A71 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S846 Y846 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]