iPTMnet Report for P98083 (Shc1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P98083 / SHC1_MOUSE
Protein Name SHC-transforming protein 1
Gene Name Name: Shc1
Synonyms:Shc,ShcA;
Organism Mus musculus (Mouse)

PRO ID PR:P98083
DAG View
PRO Name SHC-transforming protein 1 (mouse)
Definition An shc-transforming protein 1 that is encoded in the genome of mouse.
Short Label mSHC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P98083 (Shc1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S36 Phosphorylation P63085 (Mapk1) , Q63844 (Mapk3) phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 20566667, 23832324, 30459314, ...23766859, 26868434, 18174162, 20354186, 33760157, 9165038, 33688230, 21467074, 17431427, 20547441, 25810038, 11602589, 12763525, 29636844, 18956770, 28137876, 20053790, 21047172, 19327338, 15930121, 29624862, 29849865, 27960536
K81 Acetylation PhosphoSitePlus
S115 Phosphorylation PhosphoSitePlus
S139 Phosphorylation P20444 (Prkca) , P16054 (Prkce) phospho.ELM   PhosphoSitePlus   Signor   UniProt 19144319, 12052829
T145 Phosphorylation PhosphoSitePlus
K154 Acetylation UniProt 23806337
S264 Phosphorylation phospho.ELM 11897789
Y315 Phosphorylation PhosphoSitePlus
T324 Phosphorylation PhosphoSitePlus
S335 Phosphorylation PhosphoSitePlus
Y349 Phosphorylation P05480 (Src) phospho.ELM   PhosphoSitePlus 15592455, 14963047
Y350 Phosphorylation phospho.ELM   PhosphoSitePlus 15592455
S422 Phosphorylation PhosphoSitePlus
Y423 Phosphorylation IntAct   phospho.ELM   PhosphoSitePlus   UniProt 19144319, 14963047, 17947660, ...21183079, 15592455, 7529871
R433 Methylation PhosphoSitePlus
S449 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y205 Phosphorylation PhosphoSitePlus
Y239 Phosphorylation PhosphoSitePlus
Y240 Phosphorylation PhosphoSitePlus
Y313 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y160 Phosphorylation PhosphoSitePlus
Y194 Phosphorylation PhosphoSitePlus
Y195 Phosphorylation PhosphoSitePlus
Y268 Phosphorylation PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P98083 (Shc1) S36 Q01279 (Egfr) increased_association eFIP 18174162


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:000036644 (mINPP5D/iso:2/Phos:1) Interaction PR:P98083 (mSHC1) PRO 8643691