iPTMnet Report for P98078 (Dab2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P98078 / DAB2_MOUSE
Protein Name Disabled homolog 2
Gene Name Name: Dab2
Synonyms:Doc2;
Organism Mus musculus (Mouse)

PRO ID PR:P98078
DAG View
PRO Name disabled homolog 2 (mouse)
Definition A disabled homolog 2 that is encoded in the genome of mouse.
Short Label mDAB2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P98078 (Dab2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S24 Phosphorylation PhosphoSitePlus   RLIMS-P 24252604
S32 Phosphorylation PhosphoSitePlus
T35 Phosphorylation PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus
K67 Ubiquitination PhosphoSitePlus
S69 Phosphorylation PhosphoSitePlus
S72 Phosphorylation PhosphoSitePlus
C138 S-Nitrosylation dbSNO 20925432
K163 Ubiquitination PhosphoSitePlus
Y170 Phosphorylation PhosphoSitePlus   UniProt 21183079
K173 Ubiquitination PhosphoSitePlus
S193 Phosphorylation PhosphoSitePlus   UniProt 21183079
K205 Ubiquitination PhosphoSitePlus
K207 Ubiquitination PhosphoSitePlus
T221 Phosphorylation PhosphoSitePlus
S227 Phosphorylation PhosphoSitePlus
T229 Phosphorylation PhosphoSitePlus
S231 Phosphorylation PhosphoSitePlus
S323 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 19144319
S325 Phosphorylation PhosphoSitePlus
S326 Phosphorylation PhosphoSitePlus
T329 Phosphorylation PhosphoSitePlus
T340 Phosphorylation PhosphoSitePlus
Y342 Phosphorylation phospho.ELM   PhosphoSitePlus 15592455
K356 Ubiquitination PhosphoSitePlus
S394 Phosphorylation PhosphoSitePlus
S401 Phosphorylation phospho.ELM   PhosphoSitePlus 19144319
S418 O-Glycosylation GlyGen 32782141
S419 O-Glycosylation GlyGen 32782141
S422 O-Glycosylation GlyGen 32782141
S423 O-Glycosylation GlyGen 32782141
R441 Methylation PhosphoSitePlus
T470 Phosphorylation PhosphoSitePlus
K628 Ubiquitination PhosphoSitePlus
K647 Ubiquitination PhosphoSitePlus
K650 Ubiquitination PhosphoSitePlus
K654 Ubiquitination PhosphoSitePlus
K668 Ubiquitination PhosphoSitePlus
T671 Phosphorylation PhosphoSitePlus   UniProt 21183079
S674 Phosphorylation PhosphoSitePlus
S677 O-Glycosylation GlyGen 32782141
S678 O-Glycosylation GlyGen 32782141
Y683 Phosphorylation PhosphoSitePlus
S727 O-Glycosylation GlyGen 32782141
S727 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 19144319, 21183079
S731 Phosphorylation PhosphoSitePlus
S737 O-Glycosylation GlyGen 32782141
K738 Ubiquitination PhosphoSitePlus
S742 O-Glycosylation GlyGen 32782141
S743 O-Glycosylation GlyGen 32782141
S746 O-Glycosylation GlyGen 32782141
S749 O-Glycosylation GlyGen 32782141
S753 O-Glycosylation GlyGen 32782141
S759 Phosphorylation PhosphoSitePlus   UniProt 21183079


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation O88572 (Lrp6) S1579 P98078 (Dab2) increased_association eFIP 22491013


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:P98078-3 (mDAB2/iso:3) Interaction PR:Q8C5D8-2 (mPIAS2/iso:2) PRO 11104669
PR:Q8C5D8-2 (mPIAS2/iso:2) Interaction PR:P98078-3 (mDAB2/iso:3) PRO 11104669