iPTMnet Report P98077 SHC2

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P98077 / SHC2_HUMAN
Protein Name	SHC-transforming protein 2
Gene Name	Name: SHC2 Synonyms:SCK,SHCB;
Organism	Homo sapiens (Human)

PRO ID	PR:P98077 DAG View
PRO Name	SHC-transforming protein 2 (human)
Definition	An SHC-transforming protein 2 that is encoded in the genome of human.
Short Label	hSHC2
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P98077 (SHC2) as Substrate

P98077

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
		Phosphorylation		score1	PRO
	Y157	Phosphorylation		score1	PhosphoSitePlus
	Y305	Phosphorylation		score1	PhosphoSitePlus
	S333	Phosphorylation		score1	PhosphoSitePlus
	Y338	Phosphorylation		score3	PhosphoSitePlus UniProt	12006576
	Y339	Phosphorylation		score3	PhosphoSitePlus UniProt	12006576
	S341	Phosphorylation		score1	PhosphoSitePlus
	Y414	Phosphorylation		score3	PhosphoSitePlus UniProt	12006576
	S428	Phosphorylation		score1	PhosphoSitePlus
	S467	Phosphorylation		score1	PhosphoSitePlus

Proteoforms

	PRO ID (Short Label)	Sites	PTM Enzyme	Source	PMID
	PR:000049234 (hSHC2/PhosTyr+)	p		PRO

Proteoform PPIs

	Protein 1	Relation	Protein 2	Source	PMID
	PR:000025639 (hPEAR1/iso:1/Phos:1)	Interaction	PR:P98077 (hSHC2)	PRO	15851471

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
Y338	H338	Biomuta		DOID:363 / uterine cancer [ cosmic, icgc ]