iPTMnet Report for P85299 (PRR5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P85299 / PRR5_HUMAN
Protein Name Proline-rich protein 5
Gene Name Name: PRR5
Synonyms:PROTOR1;ORFNames:PP610;
Organism Homo sapiens (Human)

PRO ID PR:P85299
DAG View
PRO Name proline-rich protein 5 (human)
Definition A protor-1 that is encoded in the genome of human.
Short Label hPRR5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P85299 (PRR5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S11 Phosphorylation PhosphoSitePlus
S12 Phosphorylation PhosphoSitePlus
S14 Phosphorylation PhosphoSitePlus
K20 Acetylation PhosphoSitePlus
K161 Sumoylation PhosphoSitePlus
S238 Phosphorylation PhosphoSitePlus
S240 Phosphorylation O14757 (CHEK1) PhosphoSitePlus 21851590
K246 Ubiquitination PhosphoSitePlus
S252 Phosphorylation PhosphoSitePlus
S254 Phosphorylation PhosphoSitePlus
T257 Phosphorylation PhosphoSitePlus
S277 Phosphorylation PhosphoSitePlus
S282 Phosphorylation PhosphoSitePlus
S284 Phosphorylation PhosphoSitePlus
S310 Phosphorylation PhosphoSitePlus
S344 Phosphorylation PhosphoSitePlus
S355 Phosphorylation PhosphoSitePlus
R371 Methylation PhosphoSitePlus
S373 Phosphorylation PhosphoSitePlus
S376 Phosphorylation PhosphoSitePlus
S381 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T257 M257 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S355 F355 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:4606 / bile duct cancer [ cosmic ]
R371 L371 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
S381 P381 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]