iPTMnet Report for P84103 (SRSF3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P84103 / SRSF3_HUMAN
Protein Name Serine/arginine-rich splicing factor 3
Gene Name Name: SRSF3
Synonyms:SFRS3,SRP20;
Organism Homo sapiens (Human)

PRO ID PR:P84103
DAG View
PRO Name serine/arginine-rich splicing factor 3 (human)
Definition A serine/arginine-rich splicing factor 3 that is encoded in the genome of human.
Short Label hSRSF3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P84103 (SRSF3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 20068231
S5 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
C6 S-Nitrosylation dbSNO 2212679, 22126794, 26338901
C10 S-Nitrosylation dbSNO 2212679, 22126794, 26338901
K11 Acetylation PhosphoSitePlus
K11 Ubiquitination PhosphoSitePlus
Y13 Phosphorylation PhosphoSitePlus
K23 Acetylation PhosphoSitePlus   UniProt 19608861
K23 Ubiquitination PhosphoSitePlus
T24 Phosphorylation PhosphoSitePlus
R28 Methylation PhosphoSitePlus
Y32 Phosphorylation PhosphoSitePlus
Y33 Phosphorylation PhosphoSitePlus
R37 Methylation PhosphoSitePlus
R57 Methylation PhosphoSitePlus
T70 Phosphorylation PhosphoSitePlus
S81 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
K85 Acetylation PhosphoSitePlus
K85 Sumoylation PhosphoSitePlus
K85 Ubiquitination PhosphoSitePlus
R90 Methylation PhosphoSitePlus
S95 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
R98 Methylation PhosphoSitePlus
S108 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S120 Phosphorylation PhosphoSitePlus
S122 Phosphorylation PhosphoSitePlus
S124 Phosphorylation PhosphoSitePlus
S126 Phosphorylation PhosphoSitePlus
S128 Phosphorylation PhosphoSitePlus
S130 Phosphorylation PhosphoSitePlus
S138 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S140 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S148 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S150 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S152 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S154 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation PRO
S5 Phosphorylation HPRD 19413330, 20068231
Y13 Phosphorylation HPRD 20068231
T24 Phosphorylation HPRD 20068231
S81 Phosphorylation HPRD 17081983, 20068231
S95 Phosphorylation HPRD 18669648, 20068231, 17924679
S108 Phosphorylation HPRD 20068231, 20068230
S128 Phosphorylation HPRD 17081983
S130 Phosphorylation HPRD 17081983
S138 Phosphorylation HPRD 19651622, 17081983, 20068231
S140 Phosphorylation HPRD 19651622, 17081983, 20068231
S148 Phosphorylation HPRD 19651622, 17081983, 20068231
S150 Phosphorylation HPRD 19651622, 17081983
S152 Phosphorylation HPRD 19651622, 17081983


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000036339 (hSFRS3/Ac:1) acM1 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C6 F6 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K11 R11 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K23 M23 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K23 T23 Biomuta DOID:363 / uterine cancer [ cosmic ]
Y33 C33 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
R90 S90 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
R90 C90 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ]
R98 L98 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S130 F130 Biomuta DOID:4159 / skin cancer [ cosmic ]
S138 L138 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
S152 C152 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]