iPTMnet Report for P83111 (LACTB)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P83111 / LACTB_HUMAN
Protein Name Serine beta-lactamase-like protein LACTB, mitochondrial precursor
Gene Name Name: LACTB
Synonyms:MRPL56;ORFNames:UNQ843/PRO1781;
Organism Homo sapiens (Human)

PRO ID PR:P83111
DAG View
PRO Name serine beta-lactamase-like protein LACTB, mitochondrial (human)
Definition A serine beta-lactamase-like protein LACTB, mitochondrial that is encoded in the genome of human.
Short Label hLACTB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P83111 (LACTB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation phospho.ELM 17081983
S140 Phosphorylation PhosphoSitePlus
S164 Phosphorylation PhosphoSitePlus
S168 Phosphorylation PhosphoSitePlus
T170 Phosphorylation PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
Y201 Phosphorylation PhosphoSitePlus
S215 Phosphorylation PhosphoSitePlus
K228 Acetylation PhosphoSitePlus
K237 Acetylation PhosphoSitePlus
K237 Methylation PhosphoSitePlus
K243 Acetylation PhosphoSitePlus
K259 Acetylation PhosphoSitePlus
K264 Acetylation PhosphoSitePlus
K284 Ubiquitination PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
K342 Acetylation PhosphoSitePlus   UniProt 19608861
Y343 Phosphorylation PhosphoSitePlus
Y346 Phosphorylation PhosphoSitePlus
Y377 Phosphorylation IEDB   PhosphoSitePlus 35494241
K379 Acetylation PhosphoSitePlus
K380 Acetylation PhosphoSitePlus
Y388 Phosphorylation PhosphoSitePlus
S392 O-Glycosylation GlyGen 28510447, 30620550
Y393 Phosphorylation PhosphoSitePlus
Y418 Phosphorylation PhosphoSitePlus
Y473 Phosphorylation PhosphoSitePlus
S475 Phosphorylation PhosphoSitePlus
S532 Phosphorylation PhosphoSitePlus
K543 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation HPRD 17081983, 20068231
S215 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation HPRD 17081983, 20068231
S215 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y201 D201 Biomuta DOID:3565 / meningioma [ cosmic ]
S215 F215 Biomuta [ cosmic ]
K259 N259 Biomuta DOID:9256 / colorectal cancer [ icgc ]
Y377 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
K380 N380 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S475 L475 Biomuta DOID:2531 / hematologic cancer [ icgc ]
S532 N532 Biomuta [ cosmic, cosmic ]