iPTMnet Report for P82279 (CRB1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P82279 / CRUM1_HUMAN
Protein Name Protein crumbs homolog 1 precursor
Gene Name Name: CRB1
Organism Homo sapiens (Human)

PRO ID PR:P82279
DAG View
PRO Name protein crumbs homolog 1 (human)
Definition A protein crumbs homolog 1 that is encoded in the genome of human.
Short Label hCRB1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P82279 (CRB1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S721 Phosphorylation PhosphoSitePlus
T722 Phosphorylation PhosphoSitePlus
T745 O-Glycosylation GlyGen 36240223
S749 O-Glycosylation GlyGen 36240223
S758 O-Glycosylation GlyGen 36240223
T759 O-Glycosylation GlyGen 36240223
T1378 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S721 C721 Biomuta DOID:1324 / lung cancer [ cosmic ]
S721 F721 Biomuta DOID:4159 / skin cancer [ cosmic ]
T745 M745 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ]
S758 N758 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S758 C758 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T1378 A1378 Biomuta DOID:4159 / skin cancer [ cosmic ]