iPTMnet Report for P81122 (Irs2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P81122 / IRS2_MOUSE
Protein Name Insulin receptor substrate 2
Gene Name Name: Irs2
Organism Mus musculus (Mouse)

PRO ID PR:P81122
DAG View
PRO Name insulin receptor substrate 2 (mouse)
Definition An insulin receptor substrate 2 that is encoded in the genome of mouse.
Short Label mIRS2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P81122 (Irs2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
S66 Phosphorylation PhosphoSitePlus
Y76 Phosphorylation PhosphoSitePlus
T117 Phosphorylation PhosphoSitePlus
S301 Phosphorylation PhosphoSitePlus
S303 O-Glycosylation GlyGen 22645316
S303 Phosphorylation PhosphoSitePlus
S305 Phosphorylation PhosphoSitePlus
S306 Phosphorylation PhosphoSitePlus
T311 Phosphorylation PhosphoSitePlus
S339 Phosphorylation PhosphoSitePlus
S343 Phosphorylation PhosphoSitePlus
T347 Phosphorylation PhosphoSitePlus
T360 Phosphorylation PhosphoSitePlus
S362 Phosphorylation PhosphoSitePlus
S381 Phosphorylation PhosphoSitePlus
S385 Phosphorylation PhosphoSitePlus   UniProt 21183079
S388 Phosphorylation P30285 (Cdk4) PhosphoSitePlus   RLIMS-P   UniProt 26657864, 21183079
T401 Phosphorylation PhosphoSitePlus
S403 Phosphorylation PhosphoSitePlus
S425 O-Glycosylation GlyGen   PhosphoSitePlus 32782141, 22645316
S484 Phosphorylation PhosphoSitePlus
S488 Phosphorylation PhosphoSitePlus
Y500 Phosphorylation RLIMS-P 14557412
S512 Phosphorylation PhosphoSitePlus
S515 Phosphorylation PhosphoSitePlus
T517 Phosphorylation PhosphoSitePlus
S520 Phosphorylation PhosphoSitePlus
T524 Phosphorylation PhosphoSitePlus   UniProt 21183079
Y538 Phosphorylation PhosphoSitePlus
S556 Phosphorylation Q07832 (Plk1) PhosphoSitePlus 25830382
T571 Phosphorylation PhosphoSitePlus
S573 Phosphorylation PhosphoSitePlus
T575 Phosphorylation PhosphoSitePlus
T576 Phosphorylation PhosphoSitePlus
S590 Phosphorylation PhosphoSitePlus
Y594 Phosphorylation PhosphoSitePlus
S602 Phosphorylation PhosphoSitePlus
S604 Phosphorylation PhosphoSitePlus
S616 Phosphorylation Q9JLN9 (Mtor) PhosphoSitePlus 21659604
Y624 Phosphorylation P15208 (Insr) phospho.ELM   PhosphoSitePlus 9195949
Y628 Phosphorylation P15208 (Insr) phospho.ELM   PhosphoSitePlus 9195949
S635 Phosphorylation PhosphoSitePlus
Y649 Phosphorylation PhosphoSitePlus   UniProt 18034455
T653 Phosphorylation P63085 (Mapk1) PhosphoSitePlus 22028470
S660 Phosphorylation PhosphoSitePlus
S665 Phosphorylation PhosphoSitePlus
S668 Phosphorylation PhosphoSitePlus
Y671 Phosphorylation PhosphoSitePlus
S675 Phosphorylation PhosphoSitePlus
T677 Phosphorylation PhosphoSitePlus
S722 Phosphorylation PhosphoSitePlus
S723 Phosphorylation PhosphoSitePlus
S727 Phosphorylation PhosphoSitePlus
S728 Phosphorylation PhosphoSitePlus   UniProt 21183079
S732 Phosphorylation PhosphoSitePlus
Y734 Phosphorylation PhosphoSitePlus
Y758 Phosphorylation PhosphoSitePlus
S762 Phosphorylation PhosphoSitePlus
T771 Phosphorylation PhosphoSitePlus
S806 O-Glycosylation GlyGen 32782141
S808 Phosphorylation PhosphoSitePlus
Y814 Phosphorylation PhosphoSitePlus
S886 Phosphorylation PhosphoSitePlus
S907 Phosphorylation PhosphoSitePlus   UniProt 21183079
Y911 Phosphorylation PhosphoSitePlus
S924 Phosphorylation PhosphoSitePlus
S965 Phosphorylation PhosphoSitePlus
S968 Phosphorylation PhosphoSitePlus
Y970 Phosphorylation PhosphoSitePlus
S977 Phosphorylation PhosphoSitePlus
S980 Phosphorylation PhosphoSitePlus
S999 Phosphorylation PhosphoSitePlus
S1089 Phosphorylation PhosphoSitePlus
S1092 Phosphorylation PhosphoSitePlus
S1098 Phosphorylation Q07832 (Plk1) PhosphoSitePlus 25830382
S1137 Phosphorylation PhosphoSitePlus
S1138 Phosphorylation PhosphoSitePlus
T1140 Phosphorylation PhosphoSitePlus
S1143 Phosphorylation PhosphoSitePlus
T1144 O-Glycosylation GlyGen 32782141, 22645316
T1145 O-Glycosylation GlyGen 32782141
T1145 Phosphorylation PhosphoSitePlus
T1146 Phosphorylation PhosphoSitePlus
S1151 Phosphorylation PhosphoSitePlus   UniProt 21183079
S1153 Phosphorylation PhosphoSitePlus
S1163 Phosphorylation PhosphoSitePlus
S1165 Phosphorylation PhosphoSitePlus   UniProt 21183079
S1190 Phosphorylation PhosphoSitePlus
S1226 Phosphorylation PhosphoSitePlus
S1257 Phosphorylation PhosphoSitePlus
S1266 Phosphorylation PhosphoSitePlus
Y1303 Phosphorylation PhosphoSitePlus