iPTMnet Report for P80108 (GPLD1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P80108 / PHLD_HUMAN
Protein Name Phosphatidylinositol-glycan-specific phospholipase D precursor
Gene Name Name: GPLD1
Synonyms:PIGPLD1;
Organism Homo sapiens (Human)

PRO ID PR:P80108
DAG View
PRO Name phosphatidylinositol-glycan-specific phospholipase D (human)
Definition A phosphatidylinositol-glycan-specific phospholipase D that is encoded in the genome of human.
Short Label hGPLD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P80108 (GPLD1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N94 N-Glycosylation GlyGen   UniProt 16335952, 23090970
T231 Phosphorylation PhosphoSitePlus
S233 Phosphorylation PhosphoSitePlus
T234 Phosphorylation PhosphoSitePlus
N307 N-Glycosylation GlyGen 23090970, 29391424
N321 N-Glycosylation GlyGen 23090970, 29741879, 29391424
S491 Phosphorylation PhosphoSitePlus
N568 N-Glycosylation GlyGen 29741879, 29671580, 29391424, ...24190977
S639 Phosphorylation PhosphoSitePlus
N659 N-Glycosylation GlyGen   UniProt 19159218, 24190977, 23090970, ...29391424, 29741879, 29671580
T683 Phosphorylation PhosphoSitePlus
K764 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N568 N-Glycosylation PRO 29671580
N659 N-Glycosylation PRO 29671580


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T231 A231 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
N321 S321 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S639 C639 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
N659 T659 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T683 S683 Biomuta DOID:184 / bone cancer [ cosmic ]