Protein Information

Cytoscape View


UniProt AC / UniProt ID P78563 / RED1_HUMAN
Protein Name Double-stranded RNA-specific editase 1
Gene Name Name: ADARB1
Synonyms:ADAR2;
Organism Homo sapiens (Human)

PRO ID PR:P78563
DAG View
PRO Name double-stranded RNA-specific editase 1 (human)
Definition A double-stranded RNA-specific editase 1 that is encoded in the genome of human.
Short Label hADARB1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P78563 (ADARB1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S26 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 15302935, 20068231
S31 Phosphorylation PhosphoSitePlus
T32 Phosphorylation PhosphoSitePlus
S39 Phosphorylation PhosphoSitePlus
S42 Phosphorylation PhosphoSitePlus
S59 Phosphorylation PhosphoSitePlus
S149 Phosphorylation PhosphoSitePlus   UniProt 23186163
S211 Phosphorylation PhosphoSitePlus   RLIMS-P 29694894
S216 Phosphorylation PhosphoSitePlus   RLIMS-P 29694894
S344 Phosphorylation PhosphoSitePlus
S370 Phosphorylation PhosphoSitePlus
T375 Phosphorylation PhosphoSitePlus
S424 Phosphorylation PhosphoSitePlus
K428 Ubiquitination PhosphoSitePlus
S429 Phosphorylation PhosphoSitePlus
K523 Sumoylation PhosphoSitePlus
T530 Phosphorylation PhosphoSitePlus
T553 Phosphorylation PhosphoSitePlus
K669 Methylation PhosphoSitePlus
K691 Ubiquitination PhosphoSitePlus
Y708 Phosphorylation PhosphoSitePlus
T717 Phosphorylation PhosphoSitePlus
T740 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S26 Phosphorylation HPRD 18669648, 15302935, 20068231
S59 Phosphorylation HPRD 20068231
Y65 Phosphorylation HPRD 20068231
T304 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S26 Phosphorylation HPRD 18669648, 15302935, 20068231
S59 Phosphorylation HPRD 20068231
Y65 Phosphorylation HPRD 20068231
T304 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S26 Phosphorylation HPRD 18669648, 15302935, 20068231
S59 Phosphorylation HPRD 20068231
Y65 Phosphorylation HPRD 20068231
T304 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S26 P26 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T32 A32 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S39 P39 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S42 F42 Biomuta DOID:4159 / skin cancer [ cosmic ]
S149 Y149 Biomuta DOID:363 / uterine cancer [ icgc ]
T304 M304 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S370 R370 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T375 A375 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S429 L429 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S429 A429 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
T530 M530 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
K669 N669 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, cosmic, cosmic, cosmic ] DOID:363 / uterine cancer [ cosmic, icgc, cosmic, icgc ]