Protein Information

Cytoscape View


UniProt AC / UniProt ID P78559 / MAP1A_HUMAN
Protein Name Microtubule-associated protein 1A
Gene Name Name: MAP1A
Synonyms:MAP1L;
Organism Homo sapiens (Human)

PRO ID PR:P78559
DAG View
PRO Name microtubule-associated protein 1A (human)
Definition A microtubule-associated protein 1A that is encoded in the genome of human.
Short Label hMAP1A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P78559 (MAP1A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K37 Ubiquitination PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
S114 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
S117 Phosphorylation PhosphoSitePlus   UniProt 23186163
S118 Phosphorylation PhosphoSitePlus
S119 Phosphorylation PhosphoSitePlus
Y120 Phosphorylation PhosphoSitePlus
S121 Phosphorylation PhosphoSitePlus
S129 Phosphorylation PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
S155 Phosphorylation PhosphoSitePlus
Y177 Phosphorylation PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
K207 Ubiquitination PhosphoSitePlus
S209 Phosphorylation PhosphoSitePlus
K218 Ubiquitination PhosphoSitePlus
S223 Phosphorylation PhosphoSitePlus
K226 Ubiquitination PhosphoSitePlus
T227 Phosphorylation PhosphoSitePlus
T259 Phosphorylation PhosphoSitePlus
K275 Ubiquitination PhosphoSitePlus
K282 Ubiquitination PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
S319 Phosphorylation PhosphoSitePlus
S322 Phosphorylation PhosphoSitePlus
T382 Phosphorylation PhosphoSitePlus
S384 Phosphorylation PhosphoSitePlus
K394 Acetylation PhosphoSitePlus
K397 Acetylation PhosphoSitePlus
K403 Acetylation PhosphoSitePlus
K431 Acetylation PhosphoSitePlus
K448 Acetylation PhosphoSitePlus
K453 Acetylation PhosphoSitePlus
S460 Phosphorylation PhosphoSitePlus
T468 Phosphorylation PhosphoSitePlus
S500 Phosphorylation PhosphoSitePlus
T504 Phosphorylation PhosphoSitePlus   UniProt 23186163
S518 Phosphorylation PhosphoSitePlus
S526 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983
S527 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983
T532 Phosphorylation PhosphoSitePlus
K539 Acetylation PhosphoSitePlus
T576 Phosphorylation PhosphoSitePlus
S605 Phosphorylation PhosphoSitePlus   UniProt 23186163
S612 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...19690332
T616 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...19690332
T622 Phosphorylation PhosphoSitePlus
S644 Phosphorylation PhosphoSitePlus   UniProt 23186163
S667 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
T675 Phosphorylation PhosphoSitePlus
Y681 Phosphorylation PhosphoSitePlus
T692 Phosphorylation PhosphoSitePlus
S771 Phosphorylation PhosphoSitePlus
T772 Phosphorylation PhosphoSitePlus
Y773 Phosphorylation PhosphoSitePlus
S787 Phosphorylation PhosphoSitePlus   UniProt 23186163
T804 Phosphorylation PhosphoSitePlus
T873 O-Glycosylation GlyGen 30379171, 35132862, 28657654
S874 O-Glycosylation GlyGen 30379171, 35132862, 28657654
S874 Phosphorylation PhosphoSitePlus
S877 O-Glycosylation GlyGen 30379171, 35132862, 28657654
S878 O-Glycosylation GlyGen 30379171, 35132862, 28657654
S891 Phosphorylation PhosphoSitePlus
T894 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S896 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
T898 Phosphorylation PhosphoSitePlus
S899 Phosphorylation PhosphoSitePlus
S900 Phosphorylation PhosphoSitePlus
S909 Phosphorylation PhosphoSitePlus   UniProt 23186163
S916 Phosphorylation PhosphoSitePlus
T918 Phosphorylation PhosphoSitePlus
C955 Methylation IEDB 31844290
S956 Phosphorylation PhosphoSitePlus
Y958 Phosphorylation PhosphoSitePlus
T960 Phosphorylation PhosphoSitePlus
S964 Phosphorylation PhosphoSitePlus
S986 Phosphorylation PhosphoSitePlus   UniProt 23186163
S996 Phosphorylation PhosphoSitePlus
S1000 Phosphorylation PhosphoSitePlus
S1004 Phosphorylation PhosphoSitePlus
T1006 Phosphorylation PhosphoSitePlus
T1008 Phosphorylation PhosphoSitePlus
S1013 Phosphorylation PhosphoSitePlus
S1029 Phosphorylation PhosphoSitePlus
T1036 Phosphorylation PhosphoSitePlus
T1057 Phosphorylation PhosphoSitePlus
S1069 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
S1144 Phosphorylation PhosphoSitePlus
S1146 Phosphorylation PhosphoSitePlus
S1152 Phosphorylation PhosphoSitePlus
S1160 Phosphorylation PhosphoSitePlus   UniProt 19690332
T1163 Phosphorylation PhosphoSitePlus
T1169 Phosphorylation PhosphoSitePlus
S1172 Phosphorylation PhosphoSitePlus   UniProt 23186163
T1177 Phosphorylation PhosphoSitePlus
S1190 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1196 Phosphorylation PhosphoSitePlus
S1198 Phosphorylation PhosphoSitePlus
S1200 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1203 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1209 Phosphorylation PhosphoSitePlus
S1213 Phosphorylation PhosphoSitePlus
S1218 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
S1221 Phosphorylation PhosphoSitePlus
T1224 Phosphorylation PhosphoSitePlus
S1264 Phosphorylation PhosphoSitePlus
S1274 Phosphorylation PhosphoSitePlus
S1283 Phosphorylation PhosphoSitePlus
S1288 Phosphorylation PhosphoSitePlus
S1291 Phosphorylation PhosphoSitePlus
S1292 Phosphorylation PhosphoSitePlus
T1297 Phosphorylation PhosphoSitePlus
S1299 Phosphorylation PhosphoSitePlus
S1311 Phosphorylation PhosphoSitePlus
T1318 Phosphorylation PhosphoSitePlus
S1321 Phosphorylation PhosphoSitePlus
S1322 Phosphorylation PhosphoSitePlus
S1326 Phosphorylation PhosphoSitePlus   UniProt 23186163, 17081983
S1329 Phosphorylation PhosphoSitePlus   UniProt 17081983
Y1388 Phosphorylation PhosphoSitePlus
K1406 Acetylation PhosphoSitePlus
K1411 Acetylation PhosphoSitePlus
Y1555 Phosphorylation PhosphoSitePlus
S1600 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1626 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y1640 Phosphorylation PhosphoSitePlus
T1653 Phosphorylation PhosphoSitePlus
S1654 Phosphorylation PhosphoSitePlus   UniProt 19690332
T1674 Phosphorylation PhosphoSitePlus
S1675 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
Y1682 Phosphorylation PhosphoSitePlus
T1695 Phosphorylation PhosphoSitePlus
Y1696 Phosphorylation PhosphoSitePlus
S1701 Phosphorylation PhosphoSitePlus
Y1721 Phosphorylation PhosphoSitePlus
S1727 Phosphorylation PhosphoSitePlus
T1728 Phosphorylation PhosphoSitePlus
T1747 Phosphorylation PhosphoSitePlus
S1749 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1761 Phosphorylation PhosphoSitePlus
S1762 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1776 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
S1791 Phosphorylation PhosphoSitePlus   UniProt 19690332
S1797 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
S1801 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
S1812 Phosphorylation PhosphoSitePlus
S1818 Phosphorylation PhosphoSitePlus   UniProt 23186163
T1834 Phosphorylation PhosphoSitePlus
T1835 Phosphorylation PhosphoSitePlus
S1837 Phosphorylation PhosphoSitePlus
S1858 Phosphorylation PhosphoSitePlus
T1865 Phosphorylation PhosphoSitePlus
Y1883 Phosphorylation PhosphoSitePlus
Y1902 Phosphorylation PhosphoSitePlus
S1903 Phosphorylation PhosphoSitePlus
Y1909 Phosphorylation PhosphoSitePlus
T1957 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y1959 Phosphorylation PhosphoSitePlus
S1964 Phosphorylation PhosphoSitePlus
Y1971 Phosphorylation PhosphoSitePlus
S2012 Phosphorylation PhosphoSitePlus
S2018 Phosphorylation PhosphoSitePlus
S2019 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S2022 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 15144186, ...19690332
T2042 Phosphorylation neXtProt 22028470
T2042 Phosphorylation P28482 (MAPK1) neXtProt 22028470
S2052 Phosphorylation PhosphoSitePlus
S2056 Phosphorylation PhosphoSitePlus
T2058 Phosphorylation PhosphoSitePlus
S2074 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983
S2085 Phosphorylation PhosphoSitePlus
S2090 Phosphorylation PhosphoSitePlus
S2092 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S2104 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
T2105 Phosphorylation PhosphoSitePlus
S2106 Phosphorylation PhosphoSitePlus   UniProt 23186163
S2108 Phosphorylation PhosphoSitePlus
S2182 Phosphorylation PhosphoSitePlus
S2188 Phosphorylation PhosphoSitePlus
S2193 Phosphorylation PhosphoSitePlus
S2197 Phosphorylation PhosphoSitePlus
T2210 Phosphorylation PhosphoSitePlus
Y2217 Phosphorylation PhosphoSitePlus
T2221 O-Glycosylation GlyGen 30379171, 35132862, 28657654
S2235 Phosphorylation PhosphoSitePlus
S2238 Phosphorylation PhosphoSitePlus
S2252 Phosphorylation PhosphoSitePlus
S2256 Phosphorylation PhosphoSitePlus
S2259 Phosphorylation PhosphoSitePlus
S2366 Phosphorylation PhosphoSitePlus
S2408 Phosphorylation PhosphoSitePlus
S2419 Phosphorylation neXtProt 22028470
S2419 Phosphorylation P28482 (MAPK1) neXtProt 22028470
S2425 Phosphorylation PhosphoSitePlus
S2427 Phosphorylation PhosphoSitePlus
S2449 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
S2451 Phosphorylation PhosphoSitePlus
S2467 Phosphorylation PhosphoSitePlus
S2533 Phosphorylation PhosphoSitePlus
S2571 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
K2612 Acetylation PhosphoSitePlus
K2614 Acetylation PhosphoSitePlus
S2617 Phosphorylation PhosphoSitePlus
R2628 Methylation PhosphoSitePlus
S2629 Phosphorylation PhosphoSitePlus
T2631 Phosphorylation PhosphoSitePlus
S2649 Phosphorylation PhosphoSitePlus   UniProt 23186163
T2655 Phosphorylation PhosphoSitePlus
S2664 Phosphorylation PhosphoSitePlus   UniProt 23186163
S2667 Phosphorylation PhosphoSitePlus
S2682 Phosphorylation PhosphoSitePlus
S2683 Phosphorylation PhosphoSitePlus
K2684 Ubiquitination PhosphoSitePlus
K2705 Ubiquitination PhosphoSitePlus
T2706 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S114 Phosphorylation HPRD 17525332
T504 Phosphorylation HPRD 19413330, 19664994
S526 Phosphorylation HPRD 19651622, 17081983
S527 Phosphorylation HPRD 19651622, 17081983
T571 Phosphorylation HPRD 17081983
S612 Phosphorylation HPRD 18510355, 19651622, 17081983, ...19415658
T616 Phosphorylation HPRD 19651622, 17081983, 19415658
S667 Phosphorylation HPRD 18510355, 19651622
T675 Phosphorylation HPRD 18510355
Y773 Phosphorylation HPRD 15592455
S896 Phosphorylation HPRD 18510355
T898 Phosphorylation HPRD 17081983
S899 Phosphorylation HPRD 18510355, 17081983
S900 Phosphorylation HPRD 18510355, 17081983
S996 Phosphorylation HPRD 18510355
S1013 Phosphorylation HPRD 18510355
S1069 Phosphorylation HPRD 18491316
S1203 Phosphorylation HPRD 19651622
S1218 Phosphorylation HPRD 19413330
S1288 Phosphorylation HPRD 19651622
S1326 Phosphorylation HPRD 18510355, 19413330, 17081983, ...19651622
S1329 Phosphorylation HPRD 17081983
S1654 Phosphorylation HPRD 19651622, 19664994, 20068231
T1674 Phosphorylation HPRD 19651622
S1675 Phosphorylation HPRD 19651622, 19664994, 19415658
S1762 Phosphorylation HPRD 19651622
S1776 Phosphorylation HPRD 19651622, 19664994
S1797 Phosphorylation HPRD 19651622
S1801 Phosphorylation HPRD 18510355, 19651622
S1818 Phosphorylation HPRD 19413330, 19651622, 19415658
S2018 Phosphorylation HPRD 19415658
S2019 Phosphorylation HPRD 19413330, 19415658, 15144186
S2022 Phosphorylation HPRD 19413330, 19415658, 15144186
S2074 Phosphorylation HPRD 17081983
S2083 Phosphorylation HPRD 17081983
S2085 Phosphorylation HPRD 17081983
S2090 Phosphorylation HPRD 17081983
S2104 Phosphorylation HPRD 17081983
T2105 Phosphorylation HPRD 19651622, 17081983
S2106 Phosphorylation HPRD 19651622, 17081983
S2108 Phosphorylation HPRD 17081983
S2252 Phosphorylation HPRD 17081983
S2256 Phosphorylation HPRD 17081983
S2260 Phosphorylation HPRD 17081983
S2261 Phosphorylation HPRD 17081983
S2366 Phosphorylation HPRD 19413330


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K192 E192 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K275 N275 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K297 N297 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S460 F460 Biomuta DOID:4159 / skin cancer [ cosmic ]
S460 C460 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S527 L527 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ]
S605 N605 Biomuta DOID:363 / uterine cancer [ icgc ]
S605 R605 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T622 I622 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S644 N644 Biomuta DOID:4159 / skin cancer [ cosmic ]
T772 S772 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
Y958 H958 Biomuta DOID:1324 / lung cancer [ cosmic ]
T960 N960 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S996 Y996 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1004 R1004 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S1069 N1069 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1160 P1160 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T1163 I1163 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1172 Y1172 Biomuta DOID:363 / uterine cancer [ icgc ]
S1213 C1213 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1283 T1283 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S1288 P1288 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S1288 A1288 Biomuta DOID:363 / uterine cancer [ icgc, tcga ]
S1326 C1326 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1727 N1727 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T1728 P1728 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T1747 I1747 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1749 I1749 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
S1776 L1776 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1858 C1858 Biomuta [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
Y1959 C1959 Biomuta DOID:3953 / adrenal gland cancer [ cosmic ]
Y1971 S1971 Biomuta DOID:1612 / breast cancer [ cosmic ]
S2012 T2012 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S2012 P2012 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S2074 I2074 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S2182 F2182 Biomuta DOID:4159 / skin cancer [ cosmic ]
S2188 L2188 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S2235 L2235 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ]
S2260 Y2260 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K2612 T2612 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S2617 F2617 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S2664 I2664 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]