Protein Information

Cytoscape View


UniProt AC / UniProt ID P78527 / PRKDC_HUMAN
Protein Name DNA-dependent protein kinase catalytic subunit
Gene Name Name: PRKDC
Synonyms:HYRC,HYRC1;
Organism Homo sapiens (Human)

PRO ID PR:P78527
DAG View
PRO Name DNA-dependent protein kinase catalytic subunit (human)
Definition A DNA-dependent protein kinase catalytic subunit that is encoded in the genome of human.
Short Label hPRKDC
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P78527 (PRKDC) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R14 Methylation PhosphoSitePlus
S20 Phosphorylation PhosphoSitePlus
R24 Methylation PhosphoSitePlus
C25 S-Nitrosylation dbSNO 19483679
K71 Ubiquitination PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
C111 S-Nitrosylation dbSNO 26338901
K117 Acetylation PhosphoSitePlus   UniProt 19608861
K117 Ubiquitination PhosphoSitePlus
K124 Ubiquitination PhosphoSitePlus
T137 Phosphorylation PhosphoSitePlus
K148 Ubiquitination PhosphoSitePlus
K155 Ubiquitination PhosphoSitePlus
K163 Ubiquitination PhosphoSitePlus
K164 Ubiquitination PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
K205 Ubiquitination PhosphoSitePlus
S210 Phosphorylation PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
K225 Ubiquitination PhosphoSitePlus
K236 Ubiquitination PhosphoSitePlus
K254 Acetylation PhosphoSitePlus
K254 Ubiquitination PhosphoSitePlus
K263 Acetylation PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
K310 Ubiquitination PhosphoSitePlus
S314 Phosphorylation PhosphoSitePlus
S318 Phosphorylation PhosphoSitePlus
K321 Ubiquitination PhosphoSitePlus
K329 Ubiquitination PhosphoSitePlus
K337 Ubiquitination PhosphoSitePlus
K357 Acetylation PhosphoSitePlus
K357 Ubiquitination PhosphoSitePlus
S360 Phosphorylation PhosphoSitePlus
C373 S-Nitrosylation dbSNO 26338901
K374 Ubiquitination PhosphoSitePlus
K379 Ubiquitination PhosphoSitePlus
K393 Ubiquitination PhosphoSitePlus
T398 Phosphorylation PhosphoSitePlus
T400 Phosphorylation PhosphoSitePlus
K471 Ubiquitination PhosphoSitePlus
C478 S-Nitrosylation dbSNO 19483679
S492 Phosphorylation PhosphoSitePlus
K493 Acetylation PhosphoSitePlus
K493 Ubiquitination PhosphoSitePlus
K499 Ubiquitination PhosphoSitePlus
S503 Phosphorylation PhosphoSitePlus
S505 Phosphorylation PhosphoSitePlus
S511 Phosphorylation Q96GD4 (AURKB) PhosphoSitePlus   UniProt 22267324, 23186163
T516 Phosphorylation PhosphoSitePlus
K518 Ubiquitination PhosphoSitePlus
K520 Ubiquitination PhosphoSitePlus
K525 Ubiquitination PhosphoSitePlus
Y527 Phosphorylation PhosphoSitePlus
S552 Phosphorylation PhosphoSitePlus
K574 Ubiquitination PhosphoSitePlus
Y667 Phosphorylation PhosphoSitePlus
K681 Acetylation PhosphoSitePlus
K681 Ubiquitination PhosphoSitePlus
Y682 Phosphorylation PhosphoSitePlus
S687 Phosphorylation PhosphoSitePlus   UniProt 23186163
K689 Ubiquitination PhosphoSitePlus
K692 Ubiquitination PhosphoSitePlus
K700 Ubiquitination PhosphoSitePlus
K712 Ubiquitination PhosphoSitePlus
K717 Acetylation PhosphoSitePlus
Y721 Phosphorylation PhosphoSitePlus
Y779 Phosphorylation PhosphoSitePlus
K790 Ubiquitination PhosphoSitePlus
C795 S-Nitrosylation dbSNO 19483679
K801 Ubiquitination PhosphoSitePlus
K810 Acetylation PhosphoSitePlus
K810 Ubiquitination PhosphoSitePlus
R820 Methylation PhosphoSitePlus
K824 Ubiquitination PhosphoSitePlus
K828 Acetylation PhosphoSitePlus   UniProt 19608861
K828 Ubiquitination PhosphoSitePlus
K832 Acetylation PhosphoSitePlus
K832 Ubiquitination PhosphoSitePlus
K838 Ubiquitination PhosphoSitePlus
S841 Phosphorylation PhosphoSitePlus   UniProt 23186163
S842 Phosphorylation PhosphoSitePlus
S847 Phosphorylation PhosphoSitePlus
S861 Phosphorylation PhosphoSitePlus
K868 Ubiquitination PhosphoSitePlus
S875 Phosphorylation PhosphoSitePlus
S876 Phosphorylation PhosphoSitePlus
K881 Ubiquitination PhosphoSitePlus
S882 Phosphorylation PhosphoSitePlus
Y883 Phosphorylation PhosphoSitePlus
K890 Ubiquitination PhosphoSitePlus
S893 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 19369195, 18669648
K902 Ubiquitination PhosphoSitePlus
S922 Phosphorylation PhosphoSitePlus
T946 Phosphorylation P78527 (PRKDC) neXtProt 21300785
K963 Ubiquitination PhosphoSitePlus
T1006 Phosphorylation P78527 (PRKDC) neXtProt 21300785
K1038 Ubiquitination PhosphoSitePlus
K1042 Ubiquitination PhosphoSitePlus
K1051 Ubiquitination PhosphoSitePlus
S1052 Phosphorylation PhosphoSitePlus
K1057 Acetylation PhosphoSitePlus
K1057 Ubiquitination PhosphoSitePlus
Y1064 Phosphorylation PhosphoSitePlus
S1065 Phosphorylation PhosphoSitePlus   UniProt 23186163
K1074 Acetylation PhosphoSitePlus
K1074 Ubiquitination PhosphoSitePlus
Y1086 Phosphorylation PhosphoSitePlus
K1140 Ubiquitination PhosphoSitePlus
K1141 Ubiquitination PhosphoSitePlus
K1147 Ubiquitination PhosphoSitePlus
K1186 Ubiquitination PhosphoSitePlus
S1187 Phosphorylation PhosphoSitePlus
K1193 Ubiquitination PhosphoSitePlus
K1209 Acetylation PhosphoSitePlus   UniProt 19608861
K1209 Ubiquitination PhosphoSitePlus
T1275 Phosphorylation PhosphoSitePlus
K1311 Ubiquitination PhosphoSitePlus
C1312 S-Nitrosylation dbSNO 26338901
K1334 Ubiquitination PhosphoSitePlus
K1357 Ubiquitination PhosphoSitePlus
K1360 Ubiquitination PhosphoSitePlus
K1361 Ubiquitination PhosphoSitePlus
K1407 Ubiquitination PhosphoSitePlus
K1412 Ubiquitination PhosphoSitePlus
K1422 Ubiquitination PhosphoSitePlus
K1456 Ubiquitination PhosphoSitePlus
S1470 Phosphorylation PhosphoSitePlus
T1481 Phosphorylation PhosphoSitePlus
K1489 Ubiquitination PhosphoSitePlus
C1499 S-Nitrosylation dbSNO 19483679, 26338901
C1507 S-Nitrosylation dbSNO 19483679, 26338901
S1545 Phosphorylation PhosphoSitePlus
S1546 Phosphorylation PhosphoSitePlus
S1594 Phosphorylation PhosphoSitePlus
K1612 Ubiquitination PhosphoSitePlus
K1617 Ubiquitination PhosphoSitePlus
T1620 Phosphorylation PhosphoSitePlus
T1621 Phosphorylation PhosphoSitePlus
K1627 Ubiquitination PhosphoSitePlus
K1628 Ubiquitination PhosphoSitePlus
K1635 Ubiquitination PhosphoSitePlus
K1642 Ubiquitination PhosphoSitePlus
S1726 Phosphorylation PhosphoSitePlus
T1733 Phosphorylation PhosphoSitePlus
K1744 Ubiquitination PhosphoSitePlus
S1790 Phosphorylation PhosphoSitePlus
T1793 Phosphorylation PhosphoSitePlus
K1807 Ubiquitination PhosphoSitePlus
S1841 Phosphorylation PhosphoSitePlus
T1842 Phosphorylation PhosphoSitePlus
T1856 Phosphorylation PhosphoSitePlus
K1857 Ubiquitination PhosphoSitePlus
S1861 Phosphorylation PhosphoSitePlus
K1869 Ubiquitination PhosphoSitePlus
K1870 Ubiquitination PhosphoSitePlus
K1875 Ubiquitination PhosphoSitePlus
K1886 Ubiquitination PhosphoSitePlus
K1892 Ubiquitination PhosphoSitePlus
K1895 Ubiquitination PhosphoSitePlus
K1913 Ubiquitination PhosphoSitePlus
K1917 Ubiquitination PhosphoSitePlus
K1970 Acetylation PhosphoSitePlus   UniProt 19608861
K1970 Ubiquitination PhosphoSitePlus
K1973 Ubiquitination PhosphoSitePlus
K1985 Acetylation PhosphoSitePlus
K1985 Ubiquitination PhosphoSitePlus
K2003 Ubiquitination PhosphoSitePlus
S2023 Phosphorylation P78527 (PRKDC) neXtProt   PhosphoSitePlus 16314509
S2029 Phosphorylation P78527 (PRKDC) neXtProt   PhosphoSitePlus 16314509
S2034 Phosphorylation PhosphoSitePlus
S2041 Phosphorylation P78527 (PRKDC) neXtProt   PhosphoSitePlus 16314509
S2051 Phosphorylation PhosphoSitePlus
S2053 Phosphorylation P78527 (PRKDC) neXtProt   PhosphoSitePlus   RLIMS-P 16314509, 22972376
S2056 Phosphorylation P78527 (PRKDC) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 17189255, 23337116, 21330363, ...26208712, 25692509, 20205745, 26320609, 19071136, 26716839, 24844881, 19103741, 17438073, 25749521, 26221070, 16314509, 21390062, 26065416, 26578593, 19549901, 14734805, 21679440, 23505488, 16567133, 22977523, 22404984, 20824055, 19203584, 25223785, 21083655, 25332688, 26257651, 21567185, 22841545, 18957425, 16603769, 18559621, 17158925, 24282534, 19893054, 25307264, 15677476, 29088817, 19351595, 24952786, 20065038, 21576354, 23897887
C2093 S-Nitrosylation dbSNO 26338901
K2102 Ubiquitination PhosphoSitePlus
S2107 Phosphorylation PhosphoSitePlus
S2117 Phosphorylation PhosphoSitePlus
K2127 Ubiquitination PhosphoSitePlus
K2132 Ubiquitination PhosphoSitePlus
K2227 Ubiquitination PhosphoSitePlus
K2239 Methylation PhosphoSitePlus
K2239 Ubiquitination PhosphoSitePlus
K2246 Ubiquitination PhosphoSitePlus
S2250 Phosphorylation PhosphoSitePlus
K2259 Acetylation PhosphoSitePlus   UniProt 19608861
K2259 Ubiquitination PhosphoSitePlus
K2263 Ubiquitination PhosphoSitePlus
K2313 Ubiquitination PhosphoSitePlus
Y2329 Phosphorylation PhosphoSitePlus
K2334 Ubiquitination PhosphoSitePlus
C2342 S-Nitrosylation dbSNO 19483679
K2347 Ubiquitination PhosphoSitePlus
K2350 Ubiquitination PhosphoSitePlus
K2359 Acetylation PhosphoSitePlus
K2359 Ubiquitination PhosphoSitePlus
K2366 Ubiquitination PhosphoSitePlus
K2369 Ubiquitination PhosphoSitePlus
K2418 Ubiquitination PhosphoSitePlus
K2433 Ubiquitination PhosphoSitePlus
Y2440 Phosphorylation PhosphoSitePlus
K2441 Ubiquitination PhosphoSitePlus
K2445 Acetylation PhosphoSitePlus
K2445 Ubiquitination PhosphoSitePlus
K2447 Ubiquitination PhosphoSitePlus
K2500 Ubiquitination PhosphoSitePlus
K2503 Ubiquitination PhosphoSitePlus
T2535 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y2546 Phosphorylation PhosphoSitePlus
S2547 Phosphorylation PhosphoSitePlus
K2549 Sumoylation PhosphoSitePlus
K2549 Ubiquitination PhosphoSitePlus
S2599 Phosphorylation PhosphoSitePlus
T2600 Phosphorylation PhosphoSitePlus
T2603 Phosphorylation phospho.ELM   PhosphoSitePlus 16565220
T2609 Phosphorylation Q13535 (ATR) , P78527 (PRKDC) , Q13315 (ATM) neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   Signor   UniProt 17189255, 21330363, 12186630, ...17714814, 26320609, 15507430, 24844881, 19103741, 22189105, 17438073, 16908529, 22923485, 26578593, 19549901, 14734805, 23012265, 19583974, 24136149, 28118114, 19244120, 22404984, 24500207, 18644989, 24166892, 15258142, 18789131, 18957425, 17638905, 24021630, 16603769, 18037521, 23976954, 19893054, 15302935, 12231622, 15677476, 25223785, 26381179, 23897887, 16874298
S2612 Phosphorylation Q13315 (ATM) , P78527 (PRKDC) , Q13535 (ATR) phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   Signor   UniProt 17189255, 17525332, 25223785, ...12186630, 18077418, 15302935, 21406692, 15677476, 15258142, 24275569, 19369195, 23186163
T2615 Phosphorylation PhosphoSitePlus
T2618 Phosphorylation PhosphoSitePlus
T2620 Phosphorylation phospho.ELM   PhosphoSitePlus 15677476, 15258142, 12186630
S2624 Phosphorylation phospho.ELM   PhosphoSitePlus 15677476, 15258142, 12186630
S2626 Phosphorylation PhosphoSitePlus
T2638 Phosphorylation Q13315 (ATM) , P78527 (PRKDC) phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   Signor   UniProt 17189255, 17525332, 23186163, ...12186630, 12649176, 15302935, 15677476, 15258142
T2645 Phosphorylation PhosphoSitePlus
T2647 Phosphorylation Q13315 (ATM) , Q13535 (ATR) , P78527 (PRKDC) phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   Signor   UniProt 22404984, 17525332, 24844881, ...23186163, 12186630, 12649176, 22841545, 15302935, 15677476, 15258142, 19103741, 17438073, 16908529, 22592045, 17189255, 16874298
T2649 Phosphorylation phospho.ELM 16565220
S2654 Phosphorylation PhosphoSitePlus
S2655 Phosphorylation PhosphoSitePlus
T2671 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S2672 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S2674 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S2675 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S2677 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K2683 Acetylation PhosphoSitePlus
K2683 Ubiquitination PhosphoSitePlus
K2694 Acetylation PhosphoSitePlus
K2694 Methylation PhosphoSitePlus
K2694 Ubiquitination PhosphoSitePlus
S2695 Phosphorylation PhosphoSitePlus
K2702 Acetylation PhosphoSitePlus
K2702 Methylation PhosphoSitePlus
K2702 Ubiquitination PhosphoSitePlus
K2703 Methylation PhosphoSitePlus
K2703 Ubiquitination PhosphoSitePlus
R2704 Methylation PhosphoSitePlus
K2715 Ubiquitination PhosphoSitePlus
K2717 Ubiquitination PhosphoSitePlus
K2738 Acetylation PhosphoSitePlus
K2738 Ubiquitination PhosphoSitePlus
Y2743 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
K2746 Methylation PhosphoSitePlus
K2746 Ubiquitination PhosphoSitePlus
K2752 Ubiquitination PhosphoSitePlus
K2755 Ubiquitination PhosphoSitePlus
K2758 Sumoylation PhosphoSitePlus
K2758 Ubiquitination PhosphoSitePlus
K2764 Ubiquitination PhosphoSitePlus
K2786 Ubiquitination PhosphoSitePlus
S2789 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T2792 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K2806 Ubiquitination PhosphoSitePlus
S2814 Phosphorylation PhosphoSitePlus
K2818 Ubiquitination PhosphoSitePlus
K2824 Ubiquitination PhosphoSitePlus
S2827 Phosphorylation PhosphoSitePlus
K2829 Ubiquitination PhosphoSitePlus
K2835 Ubiquitination PhosphoSitePlus
K2908 Ubiquitination PhosphoSitePlus
K2928 Ubiquitination PhosphoSitePlus
S2932 Phosphorylation PhosphoSitePlus
Y2936 Phosphorylation PhosphoSitePlus
R2940 Methylation PhosphoSitePlus
K2950 Ubiquitination PhosphoSitePlus
S2955 Phosphorylation PhosphoSitePlus
K2970 Ubiquitination PhosphoSitePlus
K2978 Ubiquitination PhosphoSitePlus
T2987 Phosphorylation PhosphoSitePlus
K2991 Ubiquitination PhosphoSitePlus
S2998 Phosphorylation PhosphoSitePlus
S3010 Phosphorylation PhosphoSitePlus
C3014 S-Nitrosylation dbSNO 26338901
S3018 Phosphorylation PhosphoSitePlus
S3021 Phosphorylation PhosphoSitePlus
K3050 Ubiquitination PhosphoSitePlus
K3067 Ubiquitination PhosphoSitePlus
K3075 Ubiquitination PhosphoSitePlus
K3128 Ubiquitination PhosphoSitePlus
K3147 Ubiquitination PhosphoSitePlus
K3158 Ubiquitination PhosphoSitePlus
R3167 Methylation PhosphoSitePlus
K3172 Ubiquitination PhosphoSitePlus
C3187 S-Nitrosylation dbSNO 19483679
K3192 Ubiquitination PhosphoSitePlus
K3196 Ubiquitination PhosphoSitePlus
T3198 Phosphorylation PhosphoSitePlus
S3205 Phosphorylation P53350 (PLK1) , P78527 (PRKDC) phospho.ELM   PhosphoSitePlus   RLIMS-P+   RLIMS-P   Signor   UniProt 18691976, 21406692, 24844881, ...23186163, 17081983, 19369195, 12186630, 15302935, 15258142, 15677476, 18669648, 19690332, 20068231
S3215 Phosphorylation PhosphoSitePlus
R3217 Methylation PhosphoSitePlus
S3233 Phosphorylation PhosphoSitePlus
K3235 Ubiquitination PhosphoSitePlus
K3239 Acetylation PhosphoSitePlus
K3239 Ubiquitination PhosphoSitePlus
K3241 Acetylation PhosphoSitePlus   UniProt 19608861
K3241 Ubiquitination PhosphoSitePlus
K3248 Ubiquitination PhosphoSitePlus
S3253 Phosphorylation PhosphoSitePlus
K3257 Ubiquitination PhosphoSitePlus
K3260 Acetylation PhosphoSitePlus   UniProt 19608861
K3260 Ubiquitination PhosphoSitePlus
K3264 Ubiquitination PhosphoSitePlus
K3267 Acetylation PhosphoSitePlus
S3290 Phosphorylation PhosphoSitePlus
C3293 S-Nitrosylation dbSNO 2212679, 22126794
S3294 Phosphorylation PhosphoSitePlus
K3302 Ubiquitination PhosphoSitePlus
S3314 Phosphorylation PhosphoSitePlus
Y3315 Phosphorylation PhosphoSitePlus
K3318 Ubiquitination PhosphoSitePlus
C3347 S-Nitrosylation dbSNO 19483679
K3355 Acetylation PhosphoSitePlus
K3355 Ubiquitination PhosphoSitePlus
S3363 Phosphorylation PhosphoSitePlus
S3365 Phosphorylation PhosphoSitePlus
S3366 Phosphorylation PhosphoSitePlus
S3367 Phosphorylation PhosphoSitePlus
K3372 Methylation PhosphoSitePlus
K3372 Ubiquitination PhosphoSitePlus
Y3378 Phosphorylation PhosphoSitePlus
K3426 Ubiquitination PhosphoSitePlus
S3432 Phosphorylation PhosphoSitePlus
K3449 Ubiquitination PhosphoSitePlus
K3452 Ubiquitination PhosphoSitePlus
K3455 Ubiquitination PhosphoSitePlus
S3489 Phosphorylation PhosphoSitePlus
S3497 Phosphorylation PhosphoSitePlus
S3500 Phosphorylation PhosphoSitePlus
K3543 Ubiquitination PhosphoSitePlus
K3550 Ubiquitination PhosphoSitePlus
K3552 Acetylation PhosphoSitePlus
K3552 Ubiquitination PhosphoSitePlus
R3593 Methylation PhosphoSitePlus
K3598 Ubiquitination PhosphoSitePlus
T3599 Phosphorylation PhosphoSitePlus
K3608 Acetylation PhosphoSitePlus
K3608 Ubiquitination PhosphoSitePlus
K3621 Acetylation PhosphoSitePlus   UniProt 19608861
K3621 Ubiquitination PhosphoSitePlus
K3631 Ubiquitination PhosphoSitePlus
K3638 Acetylation PhosphoSitePlus   UniProt 19608861
K3638 Ubiquitination PhosphoSitePlus
K3642 Acetylation PhosphoSitePlus   UniProt 19608861
K3642 Ubiquitination PhosphoSitePlus
K3646 Ubiquitination PhosphoSitePlus
K3650 Ubiquitination PhosphoSitePlus
K3655 Ubiquitination PhosphoSitePlus
S3657 Phosphorylation PhosphoSitePlus
T3663 Phosphorylation PhosphoSitePlus
K3669 Ubiquitination PhosphoSitePlus
K3672 Ubiquitination PhosphoSitePlus
K3675 Ubiquitination PhosphoSitePlus
K3681 Ubiquitination PhosphoSitePlus
K3691 Acetylation PhosphoSitePlus
K3691 Ubiquitination PhosphoSitePlus
R3696 Methylation PhosphoSitePlus
K3710 Ubiquitination PhosphoSitePlus
Y3715 Phosphorylation PhosphoSitePlus
S3731 Phosphorylation PhosphoSitePlus   UniProt 23186163
K3753 Ubiquitination PhosphoSitePlus
S3779 Phosphorylation PhosphoSitePlus
Y3791 Phosphorylation PhosphoSitePlus
T3797 Phosphorylation PhosphoSitePlus
T3811 Phosphorylation PhosphoSitePlus
S3821 Phosphorylation PhosphoSitePlus   UniProt 23186163
K3825 Ubiquitination PhosphoSitePlus
K3840 Acetylation PhosphoSitePlus
K3840 Ubiquitination PhosphoSitePlus
K3845 Ubiquitination PhosphoSitePlus
K3849 Ubiquitination PhosphoSitePlus
Y3855 Phosphorylation PhosphoSitePlus
Y3859 Phosphorylation PhosphoSitePlus
K3860 Ubiquitination PhosphoSitePlus
T3865 Phosphorylation PhosphoSitePlus
S3870 Phosphorylation PhosphoSitePlus
K3877 Ubiquitination PhosphoSitePlus
K3884 Ubiquitination PhosphoSitePlus
T3892 Phosphorylation PhosphoSitePlus
T3950 Phosphorylation P78527 (PRKDC) neXtProt   PhosphoSitePlus   RLIMS-P   Signor 17189255, 24844881, 17158925
S3993 Phosphorylation PhosphoSitePlus
K4007 Ubiquitination PhosphoSitePlus
K4014 Ubiquitination PhosphoSitePlus
K4019 Ubiquitination PhosphoSitePlus
K4023 Ubiquitination PhosphoSitePlus
S4026 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 19369195, ...18669648, 20068231
K4036 Ubiquitination PhosphoSitePlus
K4043 Ubiquitination PhosphoSitePlus
C4045 S-Nitrosylation dbSNO 19483679
K4048 Acetylation PhosphoSitePlus
K4048 Ubiquitination PhosphoSitePlus
K4050 Ubiquitination PhosphoSitePlus
K4070 Ubiquitination PhosphoSitePlus
R4075 Methylation PhosphoSitePlus
R4082 Methylation PhosphoSitePlus
S4084 Phosphorylation PhosphoSitePlus
K4085 Ubiquitination PhosphoSitePlus
S4096 Phosphorylation PhosphoSitePlus
K4105 Ubiquitination PhosphoSitePlus
C4106 S-Nitrosylation dbSNO 26338901
Site PTM Type PTM Enzyme Score Source PMID
T137 Phosphorylation HPRD 20068231
S229 Phosphorylation HPRD 20068231
S893 Phosphorylation HPRD 18669648
S1052 Phosphorylation HPRD 18691976
T1275 Phosphorylation HPRD 20068231
S1352 Phosphorylation HPRD 20068231
T1694 Phosphorylation HPRD 20068231
T1700 Phosphorylation HPRD 20068231
S1701 Phosphorylation HPRD 20068231
T1703 Phosphorylation HPRD 20068231
S1841 Phosphorylation HPRD 18452278
T1842 Phosphorylation HPRD 18452278
S2117 Phosphorylation HPRD 18691976
Y2546 Phosphorylation HPRD 20068231
S2599 Phosphorylation HPRD 18077418
T2603 Phosphorylation HPRD 18077418, 16565220
T2609 Phosphorylation P78527 (PRKDC) HPRD 19651622, 18691976, 18077418, ...12186630, 16565220
S2612 Phosphorylation P78527 (PRKDC) HPRD 19651622, 18077418, 12186630, ...19415658, 16565220
T2620 Phosphorylation P78527 (PRKDC) HPRD 12186630
S2624 Phosphorylation P78527 (PRKDC) HPRD 12186630
T2638 Phosphorylation P78527 (PRKDC) HPRD 18077418, 12186630, 16565220
T2645 Phosphorylation HPRD 18077418
T2647 Phosphorylation P78527 (PRKDC) HPRD 18077418, 12186630, 16565220
T2649 Phosphorylation HPRD 16565220
T2671 Phosphorylation HPRD 18691976, 18669648, 20068231, ...18452278
S2672 Phosphorylation HPRD 18669648, 20068231, 18452278
S2674 Phosphorylation HPRD 18691976, 18669648, 20068231, ...18452278
S2675 Phosphorylation HPRD 18669648, 17081983, 18452278
S2677 Phosphorylation HPRD 18669648, 17081983, 18452278
Y2743 Phosphorylation HPRD 18083107
S2789 Phosphorylation HPRD 18669648
T2792 Phosphorylation HPRD 18669648
S3205 Phosphorylation P78527 (PRKDC) HPRD 18691976, 18669648, 15302935, ...20068231, 18452278
S3233 Phosphorylation HPRD 20068230
S3365 Phosphorylation HPRD 20068231
S3982 Phosphorylation HPRD 20068231
S4026 Phosphorylation HPRD 18691976, 18669648, 19664994, ...20068231, 18452278
Site PTM Type PTM Enzyme Score Source PMID
T137 Phosphorylation HPRD 20068231
S229 Phosphorylation HPRD 20068231
S893 Phosphorylation HPRD 18669648
S1052 Phosphorylation HPRD 18691976
T1275 Phosphorylation HPRD 20068231
S1352 Phosphorylation HPRD 20068231
T1694 Phosphorylation HPRD 20068231
T1700 Phosphorylation HPRD 20068231
S1701 Phosphorylation HPRD 20068231
T1703 Phosphorylation HPRD 20068231
S1841 Phosphorylation HPRD 18452278
T1842 Phosphorylation HPRD 18452278
S2117 Phosphorylation HPRD 18691976
Y2546 Phosphorylation HPRD 20068231
S2599 Phosphorylation HPRD 18077418
T2603 Phosphorylation HPRD 18077418
T2609 Phosphorylation HPRD 19651622, 18691976, 18077418
S2612 Phosphorylation HPRD 19651622, 17525332, 18077418, ...19415658
T2638 Phosphorylation HPRD 17525332, 18077418
T2645 Phosphorylation HPRD 18077418
T2647 Phosphorylation HPRD 17525332, 18077418
T2671 Phosphorylation HPRD 18691976, 18669648, 20068231, ...18452278
S2672 Phosphorylation HPRD 18669648, 20068231, 18452278
S2674 Phosphorylation HPRD 18691976, 18669648, 20068231, ...18452278
S2675 Phosphorylation HPRD 18669648, 17081983, 18452278
S2677 Phosphorylation HPRD 18669648, 17081983, 18452278
Y2743 Phosphorylation HPRD 18083107
S2789 Phosphorylation HPRD 18669648
T2792 Phosphorylation HPRD 18669648
S3205 Phosphorylation HPRD 18691976, 18669648, 17081983, ...20068231, 18452278
S3233 Phosphorylation HPRD 20068230
S3365 Phosphorylation HPRD 20068231
R3784 Methylation PhosphoSitePlus
R3802 Methylation PhosphoSitePlus
S3951 Phosphorylation HPRD 20068231
S3995 Phosphorylation HPRD 18691976, 18669648, 19664994, ...20068231, 18452278


P78527 (PRKDC) as PTM Enzyme



Substrate Site Score Source PMID
O43918 (AIRE) T68 PhosphoSitePlus 17997173
O43918 (AIRE) S156 PhosphoSitePlus 17997173
O96017 (CHEK2) T68 PhosphoSitePlus   Signor 15668230
O96017 (CHEK2) T383 PhosphoSitePlus 15668230
O96017 (CHEK2) T387 PhosphoSitePlus 15668230
P04150-2 (NR3C1) S508 HPRD 9038175
P04150-3 (NR3C1) S509 HPRD 9038175
P04637 (TP53) S9 PhosphoSitePlus 15355354, 15381073
P04637-1 (TP53) S15 HPRD   PhosphoSitePlus   Signor 9363941, 16397295, 16501611, ...10673501, 18289945, 10656682, 1406679, 10606744, 15381073, 11709713, 17339337, 15355354, 11551930, 10734067, 9765199, 12756247
P04637 (TP53) T18 HPRD   PhosphoSitePlus 15355354, 10747897, 10951572, ...11883897, 11709713
P04637-1 (TP53) S20 HPRD   PhosphoSitePlus 17339337, 10673501, 11551930, ...11709713
P04637-1 (TP53) S33 HPRD 11709713
P04637-1 (TP53) S37 HPRD   PhosphoSitePlus 9363941, 16501611, 10673501, ...15381073, 1406679, 10606744, 12756247, 11709713, 15355354, 10656682
P04637 (TP53) S46 PhosphoSitePlus 15381073
P05412 (JUN) S249 HPRD   neXtProt 19413330, 8464713, 1516134
P07900 (HSP90AA1) T5 HPRD   PhosphoSitePlus   Signor 2507541
P07900 (HSP90AA1) T7 HPRD   PhosphoSitePlus   Signor 2507541
P07900-2 (HSP90AA1) T127 HPRD 2507541
P07900-2 (HSP90AA1) T129 HPRD 2507541
P07954 (FH) T236 PhosphoSitePlus 26237645
P08670 (VIM) S56 PhosphoSitePlus 24282534
P08670 (VIM) S430 PhosphoSitePlus 24282534
P08670 (VIM) S459 PhosphoSitePlus 24282534
P11831 (SRF) S435 HPRD   neXtProt   PhosphoSitePlus 8407951
P11831 (SRF) S446 HPRD   neXtProt   PhosphoSitePlus 8407951
P12956 (XRCC6) S6 neXtProt   PhosphoSitePlus 10026262, 15941674
P12956 (XRCC6) S27 PhosphoSitePlus 26337656
P12956 (XRCC6) S33 PhosphoSitePlus 26337656
P12956 (XRCC6) S51 neXtProt   PhosphoSitePlus 10026262, 9362500
P13010 (XRCC5) S577 neXtProt   PhosphoSitePlus 10026262, 15941674
P13010 (XRCC5) S580 neXtProt   PhosphoSitePlus 10026262, 15941674
P13010 (XRCC5) T715 neXtProt   PhosphoSitePlus 10026262, 15941674
P14859 (POU2F1) S78 PhosphoSitePlus 17213819
P14859 (POU2F1) S81 PhosphoSitePlus 17213819
P14859 (POU2F1) S85 PhosphoSitePlus 17213819
P14859 (POU2F1) S88 PhosphoSitePlus 17213819
P14859 (POU2F1) S92 PhosphoSitePlus 17213819
P14859 (POU2F1) T100 PhosphoSitePlus 17213819
P14859 (POU2F1) S141 PhosphoSitePlus 17213819
P14859 (POU2F1) S143 PhosphoSitePlus 17213819
P14859 (POU2F1) S147 PhosphoSitePlus 17213819
P14859 (POU2F1) T162 PhosphoSitePlus 17213819
P14859 (POU2F1) S167 PhosphoSitePlus 17213819
P14859 (POU2F1) T226 PhosphoSitePlus   Signor 17213819, 9368058
P14859 (POU2F1) S232 PhosphoSitePlus   Signor 17213819, 9368058
P15927 (RPA2) S4 HPRD   PhosphoSitePlus 9295339, 21731742, 18289945
P15927-1 (RPA2) S8 HPRD   PhosphoSitePlus 9295339, 21731742, 18289945
P15927-1 (RPA2) S11 HPRD 9295339, 18669648
P15927-1 (RPA2) S12 HPRD   RLIMS-P+ 9295339, 22977173
P15927-1 (RPA2) S13 HPRD 9295339, 18669648
P15927-1 (RPA2) T21 HPRD   PhosphoSitePlus   Signor 9295339, 9139719, 14872059
P15927 (RPA2) S23 PhosphoSitePlus 19671522
P15927 (RPA2) S29 PhosphoSitePlus 19671522
P15927-1 (RPA2) S33 HPRD   PhosphoSitePlus 9295339, 9139719
P16403 (HIST1H1C) T146 PhosphoSitePlus 22249259
P17936 (IGFBP3) S183 PhosphoSitePlus 23557743
P18887 (XRCC1) S371 PhosphoSitePlus 16397295
P19838 (NFKB1) S20 PhosphoSitePlus 20966071
P22415 (USF1) S262 PhosphoSitePlus 23219531
P23025 (XPA) S173 HPRD   PhosphoSitePlus 16540648
P23025 (XPA) S196 HPRD   PhosphoSitePlus 16540648
P24928 (POLR2A) S1616 PhosphoSitePlus 20457598
P24928 (POLR2A) S1621 PhosphoSitePlus 20457598
P31749 (AKT1) T308 neXtProt 15678105
P31749 (AKT1) S473 neXtProt   PhosphoSitePlus   Signor 15678105, 18439899, 19144640
P31751 (AKT2) T309 neXtProt 15678105
P31751 (AKT2) S474 neXtProt 15678105
P35637 (FUS) S26 PhosphoSitePlus 18620545
P35637 (FUS) S42 PhosphoSitePlus 18620545
P35637 (FUS) S61 PhosphoSitePlus 18620545
P35637 (FUS) S84 PhosphoSitePlus 18620545
P35637 (FUS) S131 PhosphoSitePlus 18620545
P42575 (CASP2) S139 PhosphoSitePlus   Signor 19203584
P43354 (NR4A2) S337 neXtProt 21979916
P49917 (LIG4) T650 HPRD   PhosphoSitePlus   Signor 15194694
P49917 (LIG4) S668 Signor 15194694
P49917 (LIG4) S672 Signor 15194694
P52945 (PDX1) T11 PhosphoSitePlus 16166097
P55072 (VCP) S784 PhosphoSitePlus 16140914
P55895 (RAG2) S365 PhosphoSitePlus 17562296
P78527 (PRKDC) T946 neXtProt 21300785
P78527 (PRKDC) T1006 neXtProt 21300785
P78527 (PRKDC) S2023 neXtProt 16314509
P78527 (PRKDC) S2029 neXtProt 16314509
P78527 (PRKDC) S2041 neXtProt 16314509
P78527 (PRKDC) S2053 neXtProt 16314509
P78527 (PRKDC) S2056 neXtProt   PhosphoSitePlus   Signor   UniProt 17189255, 16314509, 19203584, ...17158925, 15677476, 19351595, 19103741, 14734805
P78527 (PRKDC) T2609 HPRD   neXtProt   PhosphoSitePlus   Signor   UniProt 17189255, 18691976, 12186630, ...18077418, 12231622, 15507430, 16565220, 19651622, 19103741
P78527 (PRKDC) S2612 HPRD   PhosphoSitePlus   Signor   UniProt 19369195, 12186630, 18077418, ...16565220, 19651622, 19415658
P78527-1 (PRKDC) T2620 HPRD 12186630
P78527-1 (PRKDC) S2624 HPRD 12186630
P78527-1 (PRKDC) T2638 HPRD   PhosphoSitePlus   Signor   UniProt 18077418, 12186630, 23186163, ...12649176, 16565220
P78527-1 (PRKDC) T2647 HPRD   PhosphoSitePlus   Signor   UniProt 23186163, 12186630, 18077418, ...16565220, 19103741, 12649176
P78527-1 (PRKDC) S3205 HPRD   Signor 18691976, 12186630, 15302935, ...18452278, 18669648, 20068231
P78527 (PRKDC) T3950 neXtProt   PhosphoSitePlus   Signor 17189255, 17158925
Q00839 (HNRNPU) S59 PhosphoSitePlus   Signor 19351595, 19844162
Q13426 (XRCC4) S260 PhosphoSitePlus 14599745, 12218164, 15177042
Q13426 (XRCC4) S304 PhosphoSitePlus 14599745
Q13426 (XRCC4) S320 PhosphoSitePlus 14599745, 15177042, 26666690
Q13426 (XRCC4) S327 PhosphoSitePlus 14599745
Q13426 (XRCC4) S328 PhosphoSitePlus 14599745
Q14191 (WRN) S319 PhosphoSitePlus 20516064
Q14191 (WRN) S440 PhosphoSitePlus   Signor 24429382
Q14191 (WRN) S467 PhosphoSitePlus   Signor 24429382
Q14653 (IRF3) T135 PhosphoSitePlus   Signor 11867762
Q15648 (MED1) T1457 PhosphoSitePlus 23850489
Q15831 (STK11) T363 neXtProt 12234250
Q8TCS8 (PNPT1) S776 neXtProt   PhosphoSitePlus 22815474
Q96SD1 (DCLRE1C) S503 neXtProt   PhosphoSitePlus   Signor 1660029, 16874298
Q96SD1 (DCLRE1C) S516 neXtProt   PhosphoSitePlus   Signor 16600297, 1660029, 16874298
Q96SD1 (DCLRE1C) S534 neXtProt   PhosphoSitePlus 16600297, 1660029, 16874298
Q96SD1 (DCLRE1C) S538 neXtProt   PhosphoSitePlus 16600297, 1660029, 16874298
Q96SD1 (DCLRE1C) S548 neXtProt   PhosphoSitePlus 16600297, 1660029, 16874298
Q96SD1 (DCLRE1C) S553 neXtProt   PhosphoSitePlus 16600297, 1660029, 16874298
Q96SD1 (DCLRE1C) S645 neXtProt   PhosphoSitePlus   Signor 16600297, 1660029, 16874298
Q96T60 (PNKP) S114 Signor 21824916
Q96T60 (PNKP) S126 Signor 21824916
Q9H4A6 (GOLPH3) T143 PhosphoSitePlus 24485452
Q9H4A6 (GOLPH3) T148 PhosphoSitePlus 24485452
Q9H9Q4 (NHEJ1) S55 PhosphoSitePlus 18644470
Q9H9Q4 (NHEJ1) S132 PhosphoSitePlus 18644470
Q9H9Q4 (NHEJ1) T223 PhosphoSitePlus 18644470
Q9H9Q4 (NHEJ1) S245 PhosphoSitePlus   Signor 18644470
Q9H9Q4 (NHEJ1) S251 PhosphoSitePlus 18644470
Q9H9Q4 (NHEJ1) S263 PhosphoSitePlus 18644470
Q9H9Q4 (NHEJ1) T266 PhosphoSitePlus 18644470
Q9NUW8 (TDP1) S81 PhosphoSitePlus   Signor 19851285


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048925 (hPRKDC/Phos:2) pT2609,pS2612,pT2638,pT2647 PRO


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P78527 (PRKDC) T2609 P00533 (EGFR) inhibited_association eFIP 22923485