iPTMnet Report for P78509 (RELN)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P78509 / RELN_HUMAN
Protein Name Reelin precursor
Gene Name Name: RELN
Organism Homo sapiens (Human)

PRO ID PR:P78509
DAG View
PRO Name reelin (human)
Definition A reelin that is encoded in the genome of human.
Short Label hRELN
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P78509 (RELN) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T10 Phosphorylation PhosphoSitePlus
Y29 Phosphorylation PhosphoSitePlus
Y30 Phosphorylation PhosphoSitePlus
T184 O-Glycosylation GlyGen 30459171
N257 N-Glycosylation GlyGen 29391424
S278 Phosphorylation PhosphoSitePlus
S281 Phosphorylation PhosphoSitePlus
Y286 Phosphorylation PhosphoSitePlus
N289 N-Glycosylation GlyGen 29391424
K299 Acetylation PhosphoSitePlus
N305 N-Glycosylation GlyGen   UniProt 19159218
S465 Phosphorylation PhosphoSitePlus
T468 Phosphorylation PhosphoSitePlus
Y471 Phosphorylation PhosphoSitePlus
S735 Phosphorylation PhosphoSitePlus
S743 Phosphorylation PhosphoSitePlus
S764 Phosphorylation PhosphoSitePlus
T773 Phosphorylation PhosphoSitePlus
K779 Ubiquitination PhosphoSitePlus
K833 Ubiquitination PhosphoSitePlus
Y914 Phosphorylation PhosphoSitePlus
N1266 N-Glycosylation GlyGen 29391424
S1351 Phosphorylation PhosphoSitePlus
S1355 Phosphorylation PhosphoSitePlus
Y1915 Phosphorylation PhosphoSitePlus
T1916 Phosphorylation PhosphoSitePlus
T1919 Phosphorylation PhosphoSitePlus
N1920 N-Glycosylation GlyGen   UniProt 19159218
Y2154 Phosphorylation PhosphoSitePlus
S2155 Phosphorylation PhosphoSitePlus
Y2424 Phosphorylation PhosphoSitePlus
T2434 Phosphorylation PhosphoSitePlus
T2439 Phosphorylation PhosphoSitePlus
T2820 Phosphorylation IEDB 35494241
Y2821 Phosphorylation PhosphoSitePlus
Y2952 Phosphorylation IEDB 35494241
N2961 N-Glycosylation GlyGen 29391424
N3015 N-Glycosylation GlyGen   UniProt 19159218, 29391424
N3088 N-Glycosylation GlyGen 29391424
S3108 Phosphorylation PhosphoSitePlus
Y3118 Phosphorylation PhosphoSitePlus
K3123 Acetylation PhosphoSitePlus
T3319 Phosphorylation PhosphoSitePlus
Y3435 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T773 Phosphorylation HPRD 19664995
Site PTM Type PTM Enzyme Score Source PMID
T773 Phosphorylation HPRD 19664995


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S465 Y465 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S735 R735 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S735 N735 Biomuta DOID:1324 / lung cancer [ cosmic ]
K833 R833 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
K833 T833 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T1919 I1919 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y2154 H2154 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y2154 C2154 Biomuta DOID:363 / uterine cancer [ icgc ]
Y2952 C2952 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y3118 * Biomuta DOID:1324 / lung cancer [ cosmic ]
Y3118 C3118 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y3435 C3435 Biomuta DOID:2531 / hematologic cancer [ cosmic ]