iPTMnet Report for P78504 (JAG1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P78504 / JAG1_HUMAN
Protein Name Protein jagged-1 precursor
Gene Name Name: JAG1
Synonyms:JAGL1;
Organism Homo sapiens (Human)

PRO ID PR:P78504
DAG View
PRO Name protein jagged-1 (human)
Definition A protein jagged-1 that is encoded in the genome of human.
Short Label hJAG1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P78504 (JAG1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K80 Ubiquitination PhosphoSitePlus
N217 N-Glycosylation GlyGen 23090970, 24190977
T219 Phosphorylation PhosphoSitePlus
N559 N-Glycosylation GlyGen 23090970, 24190977
S1107 Phosphorylation PhosphoSitePlus
K1123 Ubiquitination PhosphoSitePlus
K1128 Ubiquitination PhosphoSitePlus
K1137 Ubiquitination PhosphoSitePlus
Y1139 Phosphorylation PhosphoSitePlus
K1145 Acetylation PhosphoSitePlus
K1148 Acetylation PhosphoSitePlus
S1154 Phosphorylation PhosphoSitePlus
Y1176 Phosphorylation PhosphoSitePlus
T1177 Phosphorylation PhosphoSitePlus
T1189 Phosphorylation PhosphoSitePlus
K1199 Ubiquitination PhosphoSitePlus
S1210 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N217 T217 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
N559 S559 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y1176 H1176 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T1177 M1177 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T1189 M1189 Biomuta DOID:9256 / colorectal cancer [ cosmic ]