iPTMnet Report P78426 NKX6-1

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P78426 / NKX61_HUMAN
Protein Name	Homeobox protein Nkx-6.1
Gene Name	Name: NKX6-1 Synonyms:NKX6A;
Organism	Homo sapiens (Human)

PRO ID	PR:P78426 DAG View
PRO Name	homeobox protein Nkx-6.1 (human)
Definition	A homeobox protein Nkx-6.1 that is encoded in the genome of human.
Short Label	hNKX6-1
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P78426 (NKX6-1) as Substrate

P78426

Condensed View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S51	Phosphorylation		score1	PhosphoSitePlus
	S52	Phosphorylation		score1	PhosphoSitePlus
	S53	Phosphorylation		score1	PhosphoSitePlus
	S54	Phosphorylation		score1	PhosphoSitePlus
	R189	Methylation		score2	PhosphoSitePlus UniProt	24129315
	K293	Acetylation		score1	PhosphoSitePlus
	K294	Acetylation		score1	PhosphoSitePlus
	S317	Phosphorylation		score1	PhosphoSitePlus
	S334	Phosphorylation		score1	PhosphoSitePlus
	S361	Phosphorylation		score1	PhosphoSitePlus

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
R189	Q189	Biomuta		DOID:263 / kidney cancer [ cosmic, icgc ]
K293	R293	Biomuta		DOID:1319 / brain cancer [ cosmic, icgc ]