Protein Information

Cytoscape View


UniProt AC / UniProt ID P78415 / IRX3_HUMAN
Protein Name Iroquois-class homeodomain protein IRX-3
Gene Name Name: IRX3
Synonyms:IRXB1;
Organism Homo sapiens (Human)

PRO ID PR:P78415
DAG View
PRO Name iroquois-class homeodomain protein IRX-3 (human)
Definition An iroquois-class homeodomain protein IRX-3 that is encoded in the genome of human.
Short Label hIRX3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P78415 (IRX3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
S208 Phosphorylation PhosphoSitePlus
S286 Phosphorylation PhosphoSitePlus
K289 Methylation PhosphoSitePlus
K348 Sumoylation PhosphoSitePlus
S365 Phosphorylation PhosphoSitePlus
S372 Phosphorylation PhosphoSitePlus
S496 Phosphorylation PhosphoSitePlus
S499 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S286 L286 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S496 L496 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]