iPTMnet Report for P78411 (IRX5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P78411 / IRX5_HUMAN
Protein Name Iroquois-class homeodomain protein IRX-5
Gene Name Name: IRX5
Synonyms:IRX2A,IRXB2;
Organism Homo sapiens (Human)

PRO ID PR:P78411
DAG View
PRO Name iroquois-class homeodomain protein IRX-5 (human)
Definition An iroquois-class homeodomain protein IRX-5 that is encoded in the genome of human.
Short Label hIRX5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P78411 (IRX5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y3 Phosphorylation PhosphoSitePlus
Y7 Phosphorylation PhosphoSitePlus
Y9 Phosphorylation PhosphoSitePlus
Y23 Phosphorylation PhosphoSitePlus
T25 Phosphorylation PhosphoSitePlus
T180 Phosphorylation PhosphoSitePlus
S185 Phosphorylation PhosphoSitePlus
K198 Acetylation PhosphoSitePlus
T237 Phosphorylation PhosphoSitePlus
S246 Phosphorylation PhosphoSitePlus
S248 Phosphorylation PhosphoSitePlus
S274 Phosphorylation PhosphoSitePlus   UniProt 23186163
S357 Phosphorylation PhosphoSitePlus
S374 Phosphorylation PhosphoSitePlus
S377 Phosphorylation PhosphoSitePlus
S464 Phosphorylation PhosphoSitePlus   UniProt 23186163


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y7 H7 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y23 H23 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T180 M180 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S274 P274 Biomuta DOID:1324 / lung cancer [ cosmic ]