iPTMnet Report for P78395 (PRAME)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P78395 / PRAME_HUMAN
Protein Name Melanoma antigen preferentially expressed in tumors
Gene Name Name: PRAME
Synonyms:MAPE;
Organism Homo sapiens (Human)

PRO ID PR:P78395
DAG View
PRO Name melanoma antigen preferentially expressed in tumors (human)
Definition A melanoma antigen preferentially expressed in tumors that is encoded in the genome of human.
Short Label hPRAME
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P78395 (PRAME) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S9 Phosphorylation PhosphoSitePlus   UniProt 23186163
S16 Phosphorylation PhosphoSitePlus   UniProt 23186163
K118 Ubiquitination PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
K158 Acetylation PhosphoSitePlus
K158 Ubiquitination PhosphoSitePlus
K184 Acetylation PhosphoSitePlus
K198 Ubiquitination PhosphoSitePlus
K224 Ubiquitination PhosphoSitePlus
K251 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K224 N224 Biomuta [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]