iPTMnet Report for P78386 (KRT85)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P78386 / KRT85_HUMAN
Protein Name Keratin, type II cuticular Hb5
Gene Name Name: KRT85
Synonyms:KRTHB5;
Organism Homo sapiens (Human)

PRO ID PR:P78386
DAG View
PRO Name keratin, type II cuticular Hb5 (human)
Definition A keratin, type II cuticular Hb5 that is encoded in the genome of human.
Short Label hKRT85
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P78386 (KRT85) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
K149 Acetylation PhosphoSitePlus
K149 Ubiquitination PhosphoSitePlus
K229 Sumoylation PhosphoSitePlus
K229 Ubiquitination PhosphoSitePlus
K230 Ubiquitination PhosphoSitePlus
Y260 Phosphorylation PhosphoSitePlus
Y314 Phosphorylation PhosphoSitePlus
K317 Ubiquitination PhosphoSitePlus
K322 Ubiquitination PhosphoSitePlus
T324 Phosphorylation PhosphoSitePlus
T331 Phosphorylation PhosphoSitePlus
T335 Phosphorylation PhosphoSitePlus
K336 Ubiquitination PhosphoSitePlus
K384 Ubiquitination PhosphoSitePlus
K394 Ubiquitination PhosphoSitePlus
K396 Ubiquitination PhosphoSitePlus
S412 Phosphorylation PhosphoSitePlus
S493 Phosphorylation PhosphoSitePlus
S494 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S2 L2 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ]
T324 M324 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]