iPTMnet Report for P78363 (ABCA4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P78363 / ABCA4_HUMAN
Protein Name Retinal-specific phospholipid-transporting ATPase ABCA4
Gene Name Name: ABCA4
Synonyms:ABCR;
Organism Homo sapiens (Human)

PRO ID PR:P78363
DAG View
PRO Name retinal-specific phospholipid-transporting ATPase ABCA4 (human)
Definition A retinal-specific phospholipid-transporting ATPase ABCA4 that is encoded in the genome of human.
Short Label hABCA4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P78363 (ABCA4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N98 N-Glycosylation GlyGen   UniProt 33605212, 11320094
S133 Phosphorylation PhosphoSitePlus
T138 Phosphorylation PhosphoSitePlus
N415 N-Glycosylation GlyGen   UniProt 33605212, 11320094
N444 N-Glycosylation GlyGen   UniProt 33605212, 11320094
N504 N-Glycosylation GlyGen   UniProt 33605212, 11320094
T901 Phosphorylation PhosphoSitePlus
T977 Phosphorylation IEDB 35494241
S1185 Phosphorylation PhosphoSitePlus   RLIMS-P 21721517
S1282 Phosphorylation PhosphoSitePlus
T1313 Phosphorylation PhosphoSitePlus   RLIMS-P 21721517
S1317 Phosphorylation PhosphoSitePlus   RLIMS-P 21721517
N1469 N-Glycosylation GlyGen   UniProt 33605212, 11320094
N1529 N-Glycosylation GlyGen   UniProt 33605212, 11320094
S1531 O-Glycosylation GlyGen 35289036
S1531 Phosphorylation PhosphoSitePlus
N1588 N-Glycosylation GlyGen   UniProt 33605212, 11320094
T1595 Phosphorylation PhosphoSitePlus
N1662 N-Glycosylation GlyGen   UniProt 33605212, 11320094
T1930 Phosphorylation PhosphoSitePlus
S2057 Phosphorylation PhosphoSitePlus
T2061 Phosphorylation PhosphoSitePlus
Y2063 Phosphorylation PhosphoSitePlus
S2115 Phosphorylation PhosphoSitePlus
Y2203 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N1469 D1469 Biomuta DOID:363 / uterine cancer [ icgc ]
S1531 F1531 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S2115 N2115 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S2115 R2115 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]