iPTMnet Report for P78348 (ASIC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P78348 / ASIC1_HUMAN
Protein Name Acid-sensing ion channel 1
Gene Name Name: ASIC1
Synonyms:ACCN2,BNAC2;
Organism Homo sapiens (Human)

PRO ID PR:P78348
DAG View
PRO Name acid-sensing ion channel 1 (human)
Definition An acid-sensing ion channel 1 that is encoded in the genome of human.
Short Label hASIC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P78348 (ASIC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S25 Phosphorylation PhosphoSitePlus
T26 Phosphorylation RLIMS-P 19091960
S40 Phosphorylation PhosphoSitePlus   RLIMS-P 19091960
K193 Ubiquitination PhosphoSitePlus
T316 Phosphorylation PhosphoSitePlus
K374 Ubiquitination PhosphoSitePlus
S479 Phosphorylation P17612 (PRKACA) neXtProt   phospho.ELM   RLIMS-P   Signor   UniProt 12578970, 11279279
K492 Ubiquitination PhosphoSitePlus
S499 Phosphorylation PhosphoSitePlus   RLIMS-P 19091960
Site PTM Type PTM Enzyme Score Source PMID
S199 Phosphorylation PhosphoSitePlus
S525 Phosphorylation P17612 (PRKACA) HPRD   PhosphoSitePlus 12578970
S533 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S479 Phosphorylation P17612 (PRKACA) HPRD 12578970


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P78348 (ASIC1) S479 Q9NRD5 (PICK1) inhibited_association eFIP 12578970


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T316 M316 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]