iPTMnet Report for P78345 (RPP38)
Protein Information
| UniProt AC / UniProt ID | P78345 / RPP38_HUMAN |
| Protein Name | Ribonuclease P protein subunit p38 |
| Gene Name | Name: RPP38 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P78345 |
| PRO Name | ribonuclease P protein subunit p38 (human) |
| Definition | A ribonuclease P protein subunit p38 that is encoded in the genome of human. |
| Short Label | hRPP38 |
| Category | organism-gene |
P78345 (RPP38) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 19413330, 22814378 | ||
| R10 | Methylation | score1 | PhosphoSitePlus | |||
| S12 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 19413330, 23186163, 20068231 | ||
| R14 | Methylation | score1 | PhosphoSitePlus | |||
| T23 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K53 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S102 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K111 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C159 | Methylation | score1 | IEDB | 31844290 | ||
| K184 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S215 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T221 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 18669648 | ||
| S226 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 21406692, 18669648 | ||
| T234 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 18669648, 20068231, 18452278 | ||
| S235 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 23186163, 19664994, 19651622, ... | ||
| S240 | Phosphorylation | score2 | HPRD phospho.ELM | 18669648 | ||
| K241 | Acetylation | score1 | PhosphoSitePlus | |||
| K241 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S253 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T255 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| A2 | T2 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| R10 | Q10 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ] | |
| R10 | W10 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] | |
| R14 | C14 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] | |
| R14 | H14 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| T23 | M23 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic ] | |
| K111 | T111 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S226 | R226 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| T234 | I234 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] |
DAG View