Protein Information

Cytoscape View


UniProt AC / UniProt ID P78325 / ADAM8_HUMAN
Protein Name Disintegrin and metalloproteinase domain-containing protein 8 precursor
Gene Name Name: ADAM8
Synonyms:MS2;
Organism Homo sapiens (Human)

PRO ID PR:P78325
DAG View
PRO Name disintegrin and metalloproteinase domain-containing protein 8 (human)
Definition A disintegrin and metalloproteinase domain-containing protein 8 that is encoded in the genome of human.
Short Label hADAM8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P78325 (ADAM8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S48 Phosphorylation PhosphoSitePlus
N67 N-Glycosylation GlyGen 25336660, 24190977
N91 N-Glycosylation GlyGen 25336660, 30237853, 24190977
T299 Phosphorylation PhosphoSitePlus
N436 N-Glycosylation GlyGen 25336660, 24190977
N612 N-Glycosylation GlyGen 25336660, 24190977
S758 Phosphorylation PhosphoSitePlus
Y766 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N436 S436 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]