iPTMnet Report for P78325 (ADAM8)
Protein Information
| UniProt AC / UniProt ID | P78325 / ADAM8_HUMAN |
| Protein Name | Disintegrin and metalloproteinase domain-containing protein 8 precursor |
| Gene Name | Name: ADAM8 Synonyms:MS2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P78325 |
| PRO Name | disintegrin and metalloproteinase domain-containing protein 8 (human) |
| Definition | A disintegrin and metalloproteinase domain-containing protein 8 that is encoded in the genome of human. |
| Short Label | hADAM8 |
| Category | organism-gene |
P78325 (ADAM8) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S48 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N67 | N-Glycosylation | score3 | GlyGen | 25336660, 24190977 | ||
| N91 | N-Glycosylation | score3 | GlyGen | 25336660, 30237853, 24190977 | ||
| T299 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N436 | N-Glycosylation | score3 | GlyGen | 25336660, 24190977 | ||
| N612 | N-Glycosylation | score3 | GlyGen | 25336660, 24190977 | ||
| S758 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y766 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| N436 | S436 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |
DAG View