iPTMnet Report for P78325 (ADAM8)
Protein Information
UniProt AC / UniProt ID | P78325 / ADAM8_HUMAN |
Protein Name | Disintegrin and metalloproteinase domain-containing protein 8 precursor |
Gene Name | Name: ADAM8 Synonyms:MS2; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P78325 |
PRO Name | disintegrin and metalloproteinase domain-containing protein 8 (human) |
Definition | A disintegrin and metalloproteinase domain-containing protein 8 that is encoded in the genome of human. |
Short Label | hADAM8 |
Category | organism-gene |
P78325 (ADAM8) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S48 | Phosphorylation | score1 | PhosphoSitePlus | |||
N67 | N-Glycosylation | score3 | GlyGen | 25336660, 24190977 | ||
N91 | N-Glycosylation | score3 | GlyGen | 25336660, 30237853, 24190977 | ||
T299 | Phosphorylation | score1 | PhosphoSitePlus | |||
N436 | N-Glycosylation | score3 | GlyGen | 25336660, 24190977 | ||
N612 | N-Glycosylation | score3 | GlyGen | 25336660, 24190977 | ||
S758 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y766 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
N436 | S436 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |