iPTMnet Report for P78318 (IGBP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P78318 / IGBP1_HUMAN
Protein Name Immunoglobulin-binding protein 1
Gene Name Name: IGBP1
Synonyms:IBP1;
Organism Homo sapiens (Human)

PRO ID PR:P78318
DAG View
PRO Name immunoglobulin-binding protein 1 (human)
Definition An immunoglobulin-binding protein 1 that is encoded in the genome of human.
Short Label hIGBP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P78318 (IGBP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378
K41 Ubiquitination PhosphoSitePlus
K44 Ubiquitination PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
S96 Phosphorylation PhosphoSitePlus
Y145 Phosphorylation PhosphoSitePlus
S173 Phosphorylation PhosphoSitePlus
K176 Ubiquitination PhosphoSitePlus
S181 Phosphorylation PhosphoSitePlus
R225 Methylation PhosphoSitePlus
K241 Acetylation PhosphoSitePlus   UniProt 19608861
K241 Ubiquitination PhosphoSitePlus
T246 Phosphorylation PhosphoSitePlus
K253 Ubiquitination PhosphoSitePlus
Y259 Phosphorylation PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
T264 Phosphorylation PhosphoSitePlus
T266 Phosphorylation PhosphoSitePlus
S268 Phosphorylation PhosphoSitePlus
Y271 Phosphorylation PhosphoSitePlus
K276 Ubiquitination PhosphoSitePlus
Y277 Phosphorylation PhosphoSitePlus
K287 Ubiquitination PhosphoSitePlus
K295 Ubiquitination PhosphoSitePlus
K306 Ubiquitination PhosphoSitePlus
K325 Ubiquitination PhosphoSitePlus
R330 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 T2 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K253 R253 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T266 K266 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
Y277 C277 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K306 R306 Biomuta DOID:263 / kidney cancer [ cosmic ]
R330 M330 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R330 S330 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]