Protein Information

Cytoscape View


UniProt AC / UniProt ID P70336 / ROCK2_MOUSE
Protein Name Rho-associated protein kinase 2
Gene Name Name: Rock2
Organism Mus musculus (Mouse)

PRO ID PR:P70336
DAG View
PRO Name Rho-associated protein kinase 2 (mouse)
Definition A Rho-associated protein kinase 2 that is encoded in the genome of mouse.
Short Label mROCK2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P70336 (Rock2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
T7 Phosphorylation PhosphoSitePlus
T253 Phosphorylation PhosphoSitePlus
S298 Phosphorylation PhosphoSitePlus
S425 Phosphorylation PhosphoSitePlus
S439 Phosphorylation PhosphoSitePlus
T691 Phosphorylation PhosphoSitePlus
Y692 Phosphorylation PhosphoSitePlus
Y722 Phosphorylation P05480 (Src) PhosphoSitePlus 20826462
S724 Phosphorylation PhosphoSitePlus
K828 Ubiquitination PhosphoSitePlus
K1007 Acetylation PhosphoSitePlus
K1022 Acetylation PhosphoSitePlus
K1022 Ubiquitination PhosphoSitePlus
K1037 Ubiquitination PhosphoSitePlus
S1052 Phosphorylation PhosphoSitePlus
S1137 Phosphorylation UniProt 21183079
S1361 Phosphorylation PhosphoSitePlus
S1362 Phosphorylation PhosphoSitePlus
S1366 Phosphorylation PhosphoSitePlus
S1374 Phosphorylation PhosphoSitePlus   UniProt 21183079
S1379 Phosphorylation PhosphoSitePlus
S1388 Phosphorylation PhosphoSitePlus


P70336 (Rock2) as PTM Enzyme



Substrate Site Score Source PMID
P26040 (Ezr) T567 phospho.ELM   PhosphoSitePlus 9456324
P26041 (Msn) T558 phospho.ELM   PhosphoSitePlus 9456324, 9856983
P26043 (Rdx) T564 PhosphoSitePlus 9456324
P35569 (Irs1) S632 phospho.ELM   PhosphoSitePlus 16098829
P35569 (Irs1) S635 phospho.ELM   PhosphoSitePlus 16098829
P48787 (Tnni3) S23 RLIMS-P+ 15774859
P48787 (Tnni3) S24 RLIMS-P+ 15774859
P48787 (Tnni3) T144 RLIMS-P+ 15774859
Q3THE2 (Myl12b) S20 PhosphoSitePlus 17015463
Q64287 (Irf4) S446 PhosphoSitePlus 20697158
Q64287 (Irf4) S447 PhosphoSitePlus 20697158