iPTMnet Report for P69892 (HBG2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P69892 / HBG2_HUMAN
Protein Name Hemoglobin subunit gamma-2
Gene Name Name: HBG2
Organism Homo sapiens (Human)

PRO ID PR:P69892
DAG View
PRO Name hemoglobin subunit gamma-2 (human)
Definition A hemoglobin subunit gamma-2 that is encoded in the genome of human.
Short Label hHBG2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P69892 (HBG2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
G2 Acetylation UniProt 5554303
K9 Acetylation PhosphoSitePlus
K9 Ubiquitination PhosphoSitePlus
S14 Phosphorylation PhosphoSitePlus
K18 Ubiquitination PhosphoSitePlus
Y36 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
T39 Phosphorylation PhosphoSitePlus
S45 Phosphorylation PhosphoSitePlus   UniProt 23186163
S51 Phosphorylation PhosphoSitePlus   UniProt 23186163
S53 Phosphorylation PhosphoSitePlus   UniProt 23186163
K60 Acetylation PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
K62 Acetylation PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus
K66 Acetylation PhosphoSitePlus
K66 Ubiquitination PhosphoSitePlus
K67 Ubiquitination PhosphoSitePlus
K77 Acetylation PhosphoSitePlus
K77 Ubiquitination PhosphoSitePlus
K83 Acetylation PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
K96 Acetylation PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
T113 Phosphorylation PhosphoSitePlus
K133 Ubiquitination PhosphoSitePlus
T136 Phosphorylation PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus   UniProt 23186163
S143 Phosphorylation PhosphoSitePlus   UniProt 23186163
S144 Phosphorylation PhosphoSitePlus   UniProt 23186163


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
G2 D2 Biomuta DOID:10283 / prostate cancer [ icgc ]
Y36 C36 Biomuta DOID:1612 / breast cancer [ icgc ]
T39 A39 Biomuta DOID:363 / uterine cancer [ icgc ]
S51 F51 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S51 Y51 Biomuta DOID:4159 / skin cancer [ cosmic ]
K60 T60 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K67 N67 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K77 N77 Biomuta DOID:9256 / colorectal cancer [ icgc ]
K83 N83 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K96 N96 Biomuta DOID:363 / uterine cancer [ icgc ]
T136 N136 Biomuta DOID:3571 / liver cancer [ cosmic ]
S140 T140 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S144 F144 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]