iPTMnet Report for P67812 (SEC11A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P67812 / SC11A_HUMAN
Protein Name Signal peptidase complex catalytic subunit SEC11A
Gene Name Name: SEC11A
Synonyms:SEC11L1,SPC18,SPCS4A;
Organism Homo sapiens (Human)

PRO ID PR:P67812
DAG View
PRO Name signal peptidase complex catalytic subunit SEC11A (human)
Definition A signal peptidase complex catalytic subunit SEC11A that is encoded in the genome of human.
Short Label hSEC11A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P67812 (SEC11A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K100 Ubiquitination PhosphoSitePlus
K104 Ubiquitination PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
K114 Ubiquitination PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S30 Phosphorylation HPRD 20068231
S31 Phosphorylation HPRD 20068231
T43 Phosphorylation HPRD 20068231
S56 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S30 L30 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic ]
S31 L31 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S56 C56 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]