iPTMnet Report for P63220 (RPS21)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P63220 / RS21_HUMAN
Protein Name Small ribosomal subunit protein eS21
Gene Name Name: RPS21
Organism Homo sapiens (Human)

PRO ID PR:P63220
DAG View
PRO Name 40S ribosomal protein S21 (human)
Definition A 40S ribosomal protein S21 that is encoded in the genome of human.
Short Label hRPS21
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P63220 (RPS21) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation PRO   UniProt 19413330, 22814378, 22223895, ...25944712
K16 Acetylation PhosphoSitePlus
K27 Acetylation PhosphoSitePlus
K27 Ubiquitination PhosphoSitePlus
K41 Acetylation PhosphoSitePlus
K41 Sumoylation PhosphoSitePlus
K41 Ubiquitination PhosphoSitePlus
K51 Acetylation PhosphoSitePlus
K51 Methylation PhosphoSitePlus
K51 Ubiquitination PhosphoSitePlus
T52 Phosphorylation PhosphoSitePlus
Y53 Phosphorylation PhosphoSitePlus
C56 Methylation IEDB 31844290
C56 S-Nitrosylation dbSNO 26338901
S65 Phosphorylation PhosphoSitePlus
S68 Phosphorylation PhosphoSitePlus
R71 Methylation PhosphoSitePlus
K74 Ubiquitination PhosphoSitePlus
S80 Phosphorylation PhosphoSitePlus
K81 Acetylation PhosphoSitePlus   UniProt 19608861
K81 Ubiquitination PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000036167 (hRPS21/Ac:1) acM1 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K27 Q27 Biomuta DOID:1324 / lung cancer [ cosmic ]
K41 T41 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R71 * Biomuta DOID:1612 / breast cancer [ cosmic ]
K74 M74 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S80 * Biomuta DOID:4362 / cervical cancer [ cosmic ]
K81 N81 Biomuta DOID:363 / uterine cancer [ icgc ]