Protein Information

Cytoscape View


UniProt AC / UniProt ID P63218 / GBG5_HUMAN
Protein Name Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 precursor
Gene Name Name: GNG5
Synonyms:GNGT5;
Organism Homo sapiens (Human)

PRO ID PR:P63218
DAG View
PRO Name guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 (human)
Definition A guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 that is encoded in the genome of human.
Short Label hGNG5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P63218 (GNG5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330, 21406692, 12665801, ...22814378, 25944712
S2 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 20068231
S4 Phosphorylation PhosphoSitePlus
S5 Phosphorylation PhosphoSitePlus
S6 Phosphorylation PhosphoSitePlus
K12 Ubiquitination PhosphoSitePlus
R18 Methylation PhosphoSitePlus
K27 Ubiquitination PhosphoSitePlus
K36 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S2 C2 Biomuta DOID:5041 / esophageal cancer [ icgc ]
S6 R6 Biomuta DOID:9256 / colorectal cancer [ icgc ] DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
R18 L18 Biomuta DOID:1324 / lung cancer [ cosmic ]
K36 N36 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]