Protein Information

Cytoscape View

UniProt AC / UniProt ID P63165 / SUMO1_HUMAN
Protein Name Small ubiquitin-related modifier 1 precursor
Gene Name Name: SUMO1
Organism Homo sapiens (Human)

PRO ID PR:P63165
DAG View
PRO Name small ubiquitin-related modifier 1 (human)
Definition A small ubiquitin-related modifier 1 that is encoded in the genome of human.
Short Label hSUMO1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P63165 (SUMO1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330, 20388717, 21406692, ...20068231
S2 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 18691976, 21406692, 23186163, ...17081983, 18707152, 20068231
K7 Sumoylation PhosphoSitePlus
K7 Ubiquitination PhosphoSitePlus
S9 Phosphorylation PhosphoSitePlus   UniProt 20068231
T10 Phosphorylation PhosphoSitePlus
K16 Sumoylation PhosphoSitePlus
K16 Ubiquitination PhosphoSitePlus
K17 Sumoylation PhosphoSitePlus
K17 Ubiquitination PhosphoSitePlus
K23 Acetylation PhosphoSitePlus
K23 Sumoylation PhosphoSitePlus
K23 Ubiquitination PhosphoSitePlus
K25 Sumoylation PhosphoSitePlus
K25 Ubiquitination PhosphoSitePlus
S32 Phosphorylation PhosphoSitePlus   UniProt 23186163
K37 Acetylation PhosphoSitePlus
K37 Methylation PhosphoSitePlus
K37 Sumoylation PhosphoSitePlus
K37 Ubiquitination PhosphoSitePlus
K39 Methylation PhosphoSitePlus
K39 Sumoylation PhosphoSitePlus
K39 Ubiquitination PhosphoSitePlus
K45 Sumoylation PhosphoSitePlus
K45 Ubiquitination PhosphoSitePlus
K46 Sumoylation PhosphoSitePlus
K46 Ubiquitination PhosphoSitePlus
K48 Sumoylation PhosphoSitePlus
K48 Ubiquitination PhosphoSitePlus
R63 Methylation PhosphoSitePlus
R70 Methylation PhosphoSitePlus
T76 Phosphorylation PhosphoSitePlus
K78 Sumoylation PhosphoSitePlus
K78 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation HPRD 19413330, 18691976, 17081983, ...19691289, 19007248, 19651622, 18707152, 20068231
S9 Phosphorylation HPRD 19651622, 18691976, 17081983, ...20068231
T10 Phosphorylation HPRD 19651622, 17081983, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus

Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:P29590-4 (hPML/iso:4) Interaction PR:P63165 (hSUMO1) PRO 9885291

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K7 E7 Biomuta DOID:1324 / lung cancer [ tcga ]
S9 * Biomuta DOID:4362 / cervical cancer [ cosmic, icgc, tcga ]
K16 N16 Biomuta DOID:4362 / cervical cancer [ cosmic, tcga ]
R70 I70 Biomuta DOID:363 / uterine cancer [ tcga ]
R70 G70 Biomuta DOID:10534 / stomach cancer [ tcga ]
T76 N76 Biomuta DOID:3571 / liver cancer [ icgc ]