Protein Information

Cytoscape View


UniProt AC / UniProt ID P63096 / GNAI1_HUMAN
Protein Name Guanine nucleotide-binding protein G(i) subunit alpha-1
Gene Name Name: GNAI1
Organism Homo sapiens (Human)

PRO ID PR:P63096
DAG View
PRO Name guanine nucleotide-binding protein G(i) subunit alpha-1 (human)
Definition A guanine nucleotide-binding protein G(i) subunit alpha-1 that is encoded in the genome of human.
Short Label hGNAI1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P63096 (GNAI1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
G2 Myristoylation UniProt 25255805, 20213681
K17 Ubiquitination PhosphoSitePlus
K29 Ubiquitination PhosphoSitePlus
K35 Ubiquitination PhosphoSitePlus
S44 Phosphorylation PhosphoSitePlus
K46 Ubiquitination PhosphoSitePlus
K51 Ubiquitination PhosphoSitePlus
K67 Ubiquitination PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
Y154 Phosphorylation PhosphoSitePlus
Y155 Phosphorylation PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus
S206 Phosphorylation PhosphoSitePlus
K248 Ubiquitination PhosphoSitePlus
S252 Phosphorylation PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
K312 Ubiquitination PhosphoSitePlus
K317 Ubiquitination PhosphoSitePlus
Y320 Phosphorylation PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K17 N17 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S44 F44 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
K67 N67 Biomuta DOID:5041 / esophageal cancer [ tcga ]
Y155 S155 Biomuta DOID:1324 / lung cancer [ tcga ]
K317 R317 Biomuta DOID:363 / uterine cancer [ tcga ]
Y320 C320 Biomuta DOID:363 / uterine cancer [ tcga ]