iPTMnet Report for P62906 (RPL10A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P62906 / RL10A_HUMAN
Protein Name Large ribosomal subunit protein uL1
Gene Name Name: RPL10A
Synonyms:NEDD6;
Organism Homo sapiens (Human)

PRO ID PR:P62906
DAG View
PRO Name 60S ribosomal protein L10a (human)
Definition A 60S ribosomal protein L10a that is encoded in the genome of human.
Short Label hRPL10A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P62906 (RPL10A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 12962325
K4 Acetylation IEDB 29786170, 34357683
K4 Sumoylation PhosphoSitePlus
T9 Phosphorylation HPRD   PhosphoSitePlus 20068231
Y11 Phosphorylation HPRD   PhosphoSitePlus 20068231
R23 Methylation PhosphoSitePlus
S50 Phosphorylation IEDB 32897882, 29786170, 33936100, ...27920218, 30784271, 32387766, 29493099
K56 Ubiquitination PhosphoSitePlus
K62 Acetylation PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus
S64 Phosphorylation PhosphoSitePlus
C66 Methylation IEDB 31844290
K78 Ubiquitination PhosphoSitePlus
K91 Acetylation PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
K92 Acetylation PhosphoSitePlus
K106 Acetylation PhosphoSitePlus   UniProt 19608861
K106 Sumoylation PhosphoSitePlus
K106 Ubiquitination PhosphoSitePlus
Y107 Phosphorylation PhosphoSitePlus
S115 Phosphorylation PhosphoSitePlus
K118 Acetylation PhosphoSitePlus   UniProt 19608861
K118 Sumoylation PhosphoSitePlus
K118 Ubiquitination PhosphoSitePlus
K130 Ubiquitination PhosphoSitePlus
K133 Acetylation PhosphoSitePlus
K133 Ubiquitination PhosphoSitePlus
S136 Phosphorylation PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
K152 Ubiquitination PhosphoSitePlus
K156 Ubiquitination PhosphoSitePlus
C164 Methylation IEDB 31844290
K196 Ubiquitination PhosphoSitePlus
K207 Ubiquitination PhosphoSitePlus
K212 Ubiquitination PhosphoSitePlus
R215 Methylation PhosphoSitePlus
Y217 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S50 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S64 Y64 Biomuta DOID:1324 / lung cancer [ cosmic ]
C66 R66 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K133 Q133 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic, icgc ]
S136 F136 Biomuta DOID:4159 / skin cancer [ cosmic ]
C164 Y164 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R215 H215 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]