iPTMnet Report for P62879 (GNB2)
Protein Information
| UniProt AC / UniProt ID | P62879 / GBB2_HUMAN |
| Protein Name | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 |
| Gene Name | Name: GNB2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P62879 |
| PRO Name | guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (human) |
| Definition | A guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 that is encoded in the genome of human. |
| Short Label | hGNB2 |
| Category | organism-gene |
DAG ViewP62879 (GNB2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S2 | Acetylation | score1 | UniProt | 19413330 | ||
| S2 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R15 | Methylation | score1 | PhosphoSitePlus | |||
| K23 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C25 | S-Nitrosylation | score0 | dbSNO | 21278135 | ||
| T29 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T50 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K57 | Acetylation | score1 | PhosphoSitePlus | |||
| K57 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S67 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S72 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S74 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K78 | Acetylation | score1 | PhosphoSitePlus | |||
| Y85 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K89 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S136 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C204 | S-Nitrosylation | score0 | dbSNO | 26338901, 22126794, 21278135 | ||
| S207 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K209 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S216 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C218 | Methylation | score1 | IEDB | 31844290 | ||
| Y239 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K301 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C317 | S-Nitrosylation | score0 | dbSNO | 21278135 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S2 | N2 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K23 | Q23 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| C25 | R25 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| K57 | N57 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| K89 | T89 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| K89 | E89 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| K209 | N209 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |
