iPTMnet Report for P62875 (POLR2L)
Protein Information
| UniProt AC / UniProt ID | P62875 / RPAB5_HUMAN |
| Protein Name | DNA-directed RNA polymerases I, II, and III subunit RPABC5 |
| Gene Name | Name: POLR2L |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P62875 |
| PRO Name | DNA-directed RNA polymerases I, II, and III subunit RPABC5 (human) |
| Definition | A DNA-directed RNA polymerases I, II, and III subunit RPABC5 that is encoded in the genome of human. |
| Short Label | hPOLR2L |
| Category | organism-gene |
DAG ViewP62875 (POLR2L) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| C10 | Methylation | score1 | IEDB | 31844290 | ||
| K12 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K17 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K41 | Ubiquitination | score1 | PhosphoSitePlus | |||
| M48 | Methylation | score2 | IEDB | 25418920 | ||
| K58 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y62 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K67 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y62 | F62 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| K67 | R67 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
