iPTMnet Report for P62873 (GNB1)
Protein Information
| UniProt AC / UniProt ID | P62873 / GBB1_HUMAN |
| Protein Name | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 |
| Gene Name | Name: GNB1 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P62873 |
| PRO Name | guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (human) |
| Definition | A guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 that is encoded in the genome of human. |
| Short Label | hGNB1 |
| Category | organism-gene |
P62873 (GNB1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S2 | Acetylation | score1 | UniProt | 19413330, 22223895, 25944712 | ||
| S2 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K15 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R19 | Methylation | score1 | PhosphoSitePlus | |||
| R22 | Methylation | score1 | PhosphoSitePlus | |||
| K23 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S31 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T50 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K57 | Acetylation | score1 | PhosphoSitePlus | |||
| K57 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S67 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S72 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S74 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K78 | Acetylation | score1 | PhosphoSitePlus | |||
| Y85 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K89 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y111 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C121 | Methylation | score1 | IEDB | 31844290 | ||
| S136 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T143 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T159 | O-Glycosylation | score1 | GlyGen | 34019948, 34229054, 29351928 | ||
| S160 | O-Glycosylation | score1 | GlyGen | 34019948, 34229054, 29351928 | ||
| K209 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C218 | Methylation | score1 | IEDB | 31844290 | ||
| C233 | Methylation | score1 | IEDB | 31844290 | ||
| H266 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C271 | Methylation | score1 | IEDB | 31844290 | ||
| K280 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K301 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C317 | Methylation | score1 | IEDB | 31844290 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| R19 | Q19 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| R19 | L19 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| R19 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S31 | C31 | Biomuta | DOID:184 / bone cancer [ cosmic ] | |
| K57 | T57 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| K57 | E57 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| S74 | L74 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ] | |
| K78 | E78 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ] | |
| K89 | E89 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| K89 | T89 | Biomuta | DOID:1319 / brain cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] | |
| K280 | N280 | Biomuta | DOID:1319 / brain cancer [ cosmic ] |
DAG View