Protein Information

Cytoscape View


UniProt AC / UniProt ID P62837 / UB2D2_HUMAN
Protein Name Ubiquitin-conjugating enzyme E2 D2
Gene Name Name: UBE2D2
Synonyms:PUBC1,UBC4,UBC5B,UBCH4,UBCH5B;
Organism Homo sapiens (Human)

PRO ID PR:P62837
DAG View
PRO Name ubiquitin-conjugating enzyme E2 D2 (human)
Definition A ubiquitin-conjugating enzyme E2 D2 that is encoded in the genome of human.
Short Label hUBE2D2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P62837 (UBE2D2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K8 Acetylation PhosphoSitePlus
K8 Ubiquitination PhosphoSitePlus
S83 Phosphorylation PhosphoSitePlus
S94 Phosphorylation PhosphoSitePlus
T98 Phosphorylation PhosphoSitePlus
K101 Ubiquitination PhosphoSitePlus
S105 Phosphorylation PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
K144 Acetylation PhosphoSitePlus
K144 Ubiquitination PhosphoSitePlus
Y145 Phosphorylation PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P22681 (CBL) Y371 P62837 (UBE2D2) unknown eFIP 31120930


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K8 E8 Biomuta DOID:1909 / melanoma [ cosmic ]