iPTMnet Report for P62837 (UBE2D2)
Protein Information
| UniProt AC / UniProt ID | P62837 / UB2D2_HUMAN |
| Protein Name | Ubiquitin-conjugating enzyme E2 D2 |
| Gene Name | Name: UBE2D2 Synonyms:PUBC1,UBC4,UBC5B,UBCH4,UBCH5B; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P62837 |
| PRO Name | ubiquitin-conjugating enzyme E2 D2 (human) |
| Definition | A ubiquitin-conjugating enzyme E2 D2 that is encoded in the genome of human. |
| Short Label | hUBE2D2 |
| Category | organism-gene |
DAG ViewP62837 (UBE2D2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K4 | Acetylation | score1 | IEDB | 34357683 | ||
| K8 | Acetylation | score1 | PhosphoSitePlus | |||
| K8 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S83 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S94 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T98 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K101 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S105 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K128 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K144 | Acetylation | score1 | PhosphoSitePlus | |||
| K144 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y145 | Phosphorylation | score1 | PhosphoSitePlus |
PTM-dependent PPI
|
PTM type | Substrate | Site | Interactant | Association type | Source | PMID |
|---|---|---|---|---|---|---|---|
| Phosphorylation | P22681 (CBL) | Y371 | P62837 (UBE2D2) | unknown | eFIP | 31120930 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K8 | E8 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T98 | I98 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
