Protein Information

Cytoscape View

UniProt AC / UniProt ID P62834 / RAP1A_HUMAN
Protein Name Ras-related protein Rap-1A precursor
Gene Name Name: RAP1A
Organism Homo sapiens (Human)

PRO ID PR:P62834
DAG View
PRO Name Ras-related protein Rap-1A (human)
Definition A Ras-related protein Rap-1A that is encoded in the genome of human.
Short Label hRAP1A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P62834 (RAP1A) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K5 Ubiquitination PhosphoSitePlus
S11 Phosphorylation HPRD   PhosphoSitePlus 20058876
K31 Ubiquitination PhosphoSitePlus
Y32 Phosphorylation PhosphoSitePlus
S39 Phosphorylation PhosphoSitePlus
Y40 Phosphorylation PhosphoSitePlus
K117 Ubiquitination PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
K149 Ubiquitination PhosphoSitePlus
K151 Acetylation PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus
Y159 Phosphorylation PhosphoSitePlus
S180 Phosphorylation P17612 (PRKACA) HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P 9867809, 23622247

Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:Q8WWW0-2 (hRASSF5/iso:2) Interaction PR:P62834 (hRAP1A) PRO 15569673

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S11 L11 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
S39 P39 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S39 F39 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
K149 E149 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc, tcga ]
Y159 C159 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]