iPTMnet Report for P62750 (RPL23A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P62750 / RL23A_HUMAN
Protein Name Large ribosomal subunit protein uL23
Gene Name Name: RPL23A
Organism Homo sapiens (Human)

PRO ID PR:P62750
DAG View
PRO Name 60S ribosomal protein L23a (human)
Definition A 60S ribosomal protein L23a that is encoded in the genome of human.
Short Label hRPL23A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P62750 (RPL23A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K7 Ubiquitination PhosphoSitePlus
K14 Ubiquitination PhosphoSitePlus
K18 Acetylation PhosphoSitePlus
K23 Acetylation PhosphoSitePlus
K30 Ubiquitination PhosphoSitePlus
T42 O-Glycosylation GlyGen 30444036, 35138101, 32522876, ...33214551, 21740066, 34019948, 33465208
T42 Phosphorylation HPRD   PhosphoSitePlus 19691289, 20068231
S43 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18212344, 18767875, ...19691289, 19007248, 17322306, 18669648, 19415658, 20068231, 17081983
T45 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17081983, 18767875, 17322306, ...18669648, 20068231
K59 Acetylation PhosphoSitePlus
S64 Phosphorylation PhosphoSitePlus
K70 Acetylation PhosphoSitePlus
K70 Ubiquitination PhosphoSitePlus
Y74 Phosphorylation PhosphoSitePlus
K78 Acetylation PhosphoSitePlus
K78 Ubiquitination PhosphoSitePlus
S85 Phosphorylation HPRD   PhosphoSitePlus 20068231
K88 Ubiquitination PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
T95 Phosphorylation HPRD   PhosphoSitePlus 20068231
K106 Acetylation PhosphoSitePlus
K106 Ubiquitination PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
K115 Acetylation PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
Y117 Phosphorylation PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
T126 Phosphorylation PhosphoSitePlus
K134 Acetylation PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
Y137 Phosphorylation PhosphoSitePlus
Y144 Phosphorylation PhosphoSitePlus
K152 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T42 M42 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y74 C74 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
K89 N89 Biomuta DOID:1612 / breast cancer [ icgc ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K135 R135 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y137 C137 Biomuta DOID:263 / kidney cancer [ cosmic ]
Y144 D144 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]