iPTMnet Report for P62745 (RHOB)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P62745 / RHOB_HUMAN
Protein Name Rho-related GTP-binding protein RhoB precursor
Gene Name Name: RHOB
Synonyms:ARH6,ARHB;
Organism Homo sapiens (Human)

PRO ID PR:P62745
DAG View
PRO Name Rho-related GTP-binding protein RhoB (human)
Definition A Rho-related GTP-binding protein RhoB that is encoded in the genome of human.
Short Label hRHOB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P62745 (RHOB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K7 Ubiquitination PhosphoSitePlus
T19 Phosphorylation PhosphoSitePlus
S26 Phosphorylation PhosphoSitePlus
Y34 O-Glycosylation GlyGen 24141704
Y34 Phosphorylation PhosphoSitePlus
T37 O-Glycosylation UniProt 24905543
T60 Phosphorylation PhosphoSitePlus
Y66 Phosphorylation PhosphoSitePlus
K118 Ubiquitination PhosphoSitePlus
T129 Phosphorylation PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
K162 Ubiquitination PhosphoSitePlus
T173 Phosphorylation RLIMS-P 30297842
T175 Phosphorylation RLIMS-P 30297842
K181 Ubiquitination PhosphoSitePlus
S185 Phosphorylation neXtProt   PhosphoSitePlus   RLIMS-P   Signor 18590726, 27503856
S185 Phosphorylation P48729 (CSNK1A1) neXtProt   PhosphoSitePlus   Signor 18590726


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T19 R19 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T19 M19 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S26 T26 Biomuta DOID:263 / kidney cancer [ cosmic ]
Y34 C34 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K118 I118 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K135 Q135 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K162 N162 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]