iPTMnet Report for P62701 (RPS4X)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P62701 / RS4X_HUMAN
Protein Name Small ribosomal subunit protein eS4, X isoform
Gene Name Name: RPS4X
Synonyms:CCG2,RPS4,SCAR;
Organism Homo sapiens (Human)

PRO ID PR:P62701
DAG View
PRO Name 40S ribosomal protein S4, X isoform (human)
Definition A 40S ribosomal protein S4, X isoform that is encoded in the genome of human.
Short Label hRPS4X
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P62701 (RPS4X) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K7 Methylation PhosphoSitePlus
K16 Acetylation PhosphoSitePlus
K16 Ubiquitination PhosphoSitePlus
K22 Acetylation PhosphoSitePlus
K22 Ubiquitination PhosphoSitePlus
T24 Phosphorylation PhosphoSitePlus
S32 Phosphorylation PhosphoSitePlus
T33 Phosphorylation PhosphoSitePlus
K37 Acetylation PhosphoSitePlus
K37 Ubiquitination PhosphoSitePlus
C41 Methylation IEDB 31844290
C41 S-Nitrosylation dbSNO 26338901, 21278135
K53 Acetylation PhosphoSitePlus
K53 Methylation PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus
Y54 Phosphorylation PhosphoSitePlus
T57 Phosphorylation PhosphoSitePlus
K62 Acetylation PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
K75 Ubiquitination PhosphoSitePlus
T78 Phosphorylation PhosphoSitePlus
S91 Phosphorylation PhosphoSitePlus
K94 Ubiquitination PhosphoSitePlus
Y103 Phosphorylation PhosphoSitePlus
T105 Phosphorylation PhosphoSitePlus
K106 Ubiquitination PhosphoSitePlus
T115 O-Glycosylation GlyGen 33214551, 34725712, 35138101, ...30379171, 32522876, 34019948, 35083852, 32119511, 22121020
K120 Acetylation PhosphoSitePlus
K120 Ubiquitination PhosphoSitePlus
Y121 Phosphorylation PhosphoSitePlus
K125 Ubiquitination PhosphoSitePlus
K128 Acetylation PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
T133 Phosphorylation PhosphoSitePlus
K134 Acetylation PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
R145 Methylation PhosphoSitePlus
R148 Methylation PhosphoSitePlus
K168 Ubiquitination PhosphoSitePlus
K174 Sumoylation PhosphoSitePlus
T177 Phosphorylation HPRD   PhosphoSitePlus 20068231
C181 S-Nitrosylation dbSNO 26338901, 21278135
T184 Phosphorylation HPRD   PhosphoSitePlus 20068231
T196 Phosphorylation PhosphoSitePlus
R198 Methylation PhosphoSitePlus
R200 Methylation PhosphoSitePlus
S204 Phosphorylation HPRD   PhosphoSitePlus 20068231
K211 Ubiquitination PhosphoSitePlus
S217 Phosphorylation HPRD 20068231
S223 Phosphorylation PhosphoSitePlus
K230 Ubiquitination PhosphoSitePlus
K233 Acetylation PhosphoSitePlus
K233 Ubiquitination PhosphoSitePlus
S237 Phosphorylation PhosphoSitePlus
T247 Phosphorylation HPRD 19007248
K259 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T24 A24 Biomuta DOID:363 / uterine cancer [ icgc ]
S91 N91 Biomuta DOID:4159 / skin cancer [ cosmic ]
K120 N120 Biomuta DOID:1319 / brain cancer [ icgc ]
R145 H145 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R148 C148 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
R148 H148 Biomuta DOID:363 / uterine cancer [ icgc ]
T196 N196 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K230 E230 Biomuta DOID:1324 / lung cancer [ cosmic ]