iPTMnet Report for P62508 (ESRRG)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P62508 / ERR3_HUMAN
Protein Name Estrogen-related receptor gamma
Gene Name Name: ESRRG
Synonyms:ERR3,ERRG2,KIAA0832,NR3B3;
Organism Homo sapiens (Human)

PRO ID PR:P62508
DAG View
PRO Name estrogen-related receptor gamma (human)
Definition An estrogen-related receptor gamma that is encoded in the genome of human.
Short Label hESRRG
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P62508 (ESRRG) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S33 Phosphorylation PhosphoSitePlus
S34 Phosphorylation PhosphoSitePlus
S36 Phosphorylation PhosphoSitePlus
S37 Phosphorylation PhosphoSitePlus
K40 Sumoylation PhosphoSitePlus
S45 Phosphorylation PhosphoSitePlus   UniProt 19067653, 18063693
Y101 Phosphorylation PhosphoSitePlus
T114 Phosphorylation PhosphoSitePlus
S122 Phosphorylation PhosphoSitePlus
K195 Acetylation PhosphoSitePlus
K195 Ubiquitination PhosphoSitePlus
K363 Ubiquitination PhosphoSitePlus
T420 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S33 F33 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S36 L36 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S36 P36 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K40 N40 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K40 E40 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S122 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K363 N363 Biomuta DOID:4159 / skin cancer [ cosmic ]