Protein Information

Cytoscape View


UniProt AC / UniProt ID P62333 / PRS10_HUMAN
Protein Name 26S proteasome regulatory subunit 10B
Gene Name Name: PSMC6
Synonyms:SUG2;
Organism Homo sapiens (Human)

PRO ID PR:P62333
DAG View
PRO Name 26S proteasome regulatory subunit 10B (human)
Definition A 26S proteasome regulatory subunit 10B that is encoded in the genome of human.
Short Label hPSMC6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P62333 (PSMC6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K7 Ubiquitination PhosphoSitePlus
K15 Acetylation PhosphoSitePlus
K15 Ubiquitination PhosphoSitePlus
K20 Acetylation PhosphoSitePlus
K20 Ubiquitination PhosphoSitePlus
K27 Ubiquitination PhosphoSitePlus
K34 Ubiquitination PhosphoSitePlus
K38 Ubiquitination PhosphoSitePlus
K42 Ubiquitination PhosphoSitePlus
K48 Ubiquitination PhosphoSitePlus
S52 Phosphorylation PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus
K68 Acetylation PhosphoSitePlus
K68 Ubiquitination PhosphoSitePlus
K72 Acetylation PhosphoSitePlus   UniProt 19608861
K72 Ubiquitination PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
T103 Phosphorylation PhosphoSitePlus
T104 Phosphorylation PhosphoSitePlus
T106 Phosphorylation PhosphoSitePlus
S131 Phosphorylation PhosphoSitePlus
Y132 Phosphorylation PhosphoSitePlus
K168 Ubiquitination PhosphoSitePlus
Y173 Phosphorylation PhosphoSitePlus
K180 Ubiquitination PhosphoSitePlus
C193 S-Nitrosylation dbSNO 19483679
K197 Ubiquitination PhosphoSitePlus
S201 Phosphorylation PhosphoSitePlus
S202 Phosphorylation PhosphoSitePlus
K206 Acetylation PhosphoSitePlus   UniProt 19608861
K206 Ubiquitination PhosphoSitePlus
Y207 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
Y221 Phosphorylation HPRD 18083107
S244 Phosphorylation PhosphoSitePlus   UniProt 23186163
K274 Ubiquitination PhosphoSitePlus
K298 Ubiquitination PhosphoSitePlus
K314 Ubiquitination PhosphoSitePlus
K322 Ubiquitination PhosphoSitePlus
Y328 Phosphorylation PhosphoSitePlus
K333 Ubiquitination PhosphoSitePlus
K369 Ubiquitination PhosphoSitePlus
K383 Ubiquitination PhosphoSitePlus
Y386 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K91 N91 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K180 T180 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc, tcga ]
K206 R206 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]